Results 171 to 180 of about 1,070,439 (189)

Macrocyclization strategies in polyketide and nonribosomal peptide biosynthesis

Natural Product Reports, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Florian, Kopp, Mohamed A, Marahiel
openaire   +2 more sources

Biosynthetic engineering of nonribosomal peptide synthetases

Journal of Peptide Science, 2016
From the evolutionary melting pot of natural product synthetase genes, microorganisms elicit antibiotics, communication tools, and iron scavengers. Chemical biologists manipulate these genes to recreate similarly diverse and potent biological activities not on evolutionary time scales but within months. Enzyme engineering has progressed considerably in
openaire   +3 more sources

Structure, Function and Engineering of the Nonribosomal Peptide Synthetase Condensation Domain

International Journal of Molecular Sciences
The nonribosomal peptide synthetase (NRPS) is a highly precise molecular assembly machinery for synthesizing structurally diverse peptides, which have broad medicinal applications.
Zhenkuai Huang, Zijing Peng, Mengli Zhang, Xinhai Li, X. Qiu   +4 more
semanticscholar   +1 more source

Peptide Natural Products II: Nonribosomal Peptides

2022
Peptide natural products assembled by nonribosomal peptide synthetase (NRPS) machinery activate proteinogenic and nonproteinogenic amino acids, install them as thioesters tethered to phosphopantetheinyl prosthetic groups on peptidyl carrier protein domains, and carry out chain elongations by amide bond formations.
openaire   +1 more source

Characterization of Nonribosomal Peptide Synthetases with NRPSsp

2016
Bioinformatic sequence analysis allows the functional characterization of newly sequenced proteins. Nonribosomal peptide synthetases (NRPSs) are multi-modular enzymes involved in the biosynthesis of natural products. The current omics era has enabled the exponential growth of the sequenced NRPS, and it is important to characterize the final product of ...
openaire   +2 more sources

Oxepinamides L and M, two new oxepine-pyrimidinone-ketopiperazine type nonribosomal peptides from Aspergillus californicus

Natural Product Research, 2022
Simone Ghidinelli, Mercedes De La Cruz Moreno, Thomas Ostenfeld Larsen   +2 more
exaly  

Co‐occurring Congeners Reveal the Position of Enantiomeric Amino Acids in Nonribosomal Peptides

ChemBioChem, 2021
Ignacio Pérez-Victoria
exaly  

Nonribosomal peptides and polyketides of Burkholderia: new compounds potentially implicated in biocontrol and pharmaceuticals

Environmental science and pollution research international, 2018
Qassim Esmaeel, Maude Pupin, P. Jacques, V. Leclère   +3 more
semanticscholar   +1 more source

Nonribosomal Peptide Synthetases

2010
Timothy J. Montavon, Steven D. Bruner
openaire   +1 more source

Norine: Bioinformatics Methods and Tools for the Characterization of Newly Discovered Nonribosomal Peptides

Methods in Molecular Biology, 2023
Valerie Leclere, , Philippe Jacques
exaly