Results 161 to 170 of about 41,960 (230)

Predicting nonsense-mediated mRNA decay from splicing events in sepsis using RNA-sequencing data. [PDF]

Life Sci Alliance
Shin J, Fredericks AM, Armstead BE, Ayala A, Cohen M, Fairbrother WG, Levy MM, Lillard KK, Raggi E, Nau GJ, Monaghan SF.   +10 more
europepmc   +1 more source

Exploring the therapeutic potential of modulating nonsense-mediated mRNA decay. [PDF]

RNA
McMahon M, Maquat LE.
europepmc   +1 more source

UPF3A is dispensable for nonsense-mediated mRNA decay in mouse pluripotent and somatic cells. [PDF]

Life Sci Alliance, 2023
Chen C, Shen Y, Li L, Ren Y, Wang ZQ, Li T.   +5 more
europepmc   +1 more source

<i>Smg5</i> Enhances Oligodendrocyte Differentiation via Nonsense-Mediated mRNA Decay of <i>Hnrnpl</i> Variant Transcripts. [PDF]

J Neurosci
Jiang M, Li C, Xie B, Li T, Dai ZM, Qiu M.   +5 more
europepmc   +1 more source

A novel frameshift <i>STAG1</i> variant exhibiting haploinsufficiency due to the nonsense-mediated mRNA decay: a case report and literature review. [PDF]

Front Pediatr
Jiang C, Wu K, Zhou Y.
europepmc   +1 more source

Insights From Nonsense-Mediated mRNA Decay for Prognosis in Homologous Recombination-Deficient Ovarian Cancer. [PDF]

Cancer Sci
Han L, Liu J, Zhang R, Cheng Y, Dong L, Wei L, Liu J, Wang K, Yu J.   +8 more
europepmc   +1 more source

The mechanism of nonsense-mediated mRNA decay

, 2015
Nonsense-mediated mRNA decay (NMD) is a quality control pathway that recognizes and rapidly degrades mRNAs containing a premature termination codon (PTC). The prevalent model, proposes that in mammals a translation termination codon is generally interpreted as premature if it is localized more than 50-55 nucleotides upstream of the last exon-exon ...
openaire   +1 more source

A novel homozygous frameshift mutation likely causing nonsense-mediated mRNA decay in an Algerian kindred with CD19 complex deficiency. [PDF]

Front Immunol
Belaid B, Chan KW, Lamara Mahammed L, Leung D, Makhloufi S, Bendaoud F, Sakhri H, Berkani LM, Allam I, Merah F, Baaziz H, Lo B, Rosa Duque JS, Lau YL, Djidjik R.   +14 more
europepmc   +1 more source

Endonucleolytic cleavage is the primary mechanism of decay elicited by <i>C. elegans</i> nonsense-mediated mRNA decay. [PDF]

Genome Res
Viscardi MJ, Sehgal E, Arribere JA.
europepmc   +1 more source

Up-Frameshift Factors from Phytopathogenic Fungi Play a Crucial Role in Nonsense-Mediated mRNA Decay. [PDF]

J Fungi (Basel)
Lu P, Wang J, Wang X, Wang D, Shi H.
europepmc   +1 more source