Results 1 to 10 of about 435,524 (391)

Engineered tRNAs suppress nonsense mutations in cells and in vivo

open access: yesNature, 2023
Suppressor tRNAs adapted to the amino acid that they carry enable readthrough of premature termination codons introduced by nonsense mutations and show potential for the treatment of genetic diseases such as cystic fibrosis.
Nikhil Bharti, Marcos Davyt, Disha Joshi
exaly   +2 more sources

Targeted pseudouridylation: An approach for suppressing nonsense mutations in disease genes

open access: yesMolecular Cell, 2023
Nonsense mutations create premature termination codons (PTCs), activating the nonsense-mediated mRNA decay (NMD) pathway to degrade most PTC-containing mRNAs.
Pedro, Yi-Tao Yu
exaly   +2 more sources

Quality and quantity control of gene expression by nonsense-mediated mRNA decay

open access: yesNature Reviews Molecular Cell Biology, 2019
Tatsuaki Kurosaki   +2 more
exaly   +2 more sources

“Dr. Seuss of Beasts and Men: the Cartoonist’s Experience and the Illustrated Tales of the 1930–1950s [PDF]

open access: yesЛитература двух Америк, 2023
The paper deals with the first decades in the work of Dr. Seuss (the pseudonym of Theodor Geisel, 1904–1991), one of the most prominent children’s authors of the 20th century.
Nina A. Moroz
doaj   +1 more source

How to (mis)use language: humor, creativity and lexical creation in Rikki Ducornet’s The Stain, The Fountains of Neptune and Phosphor in Dreamland

open access: yesLexis: Journal in English Lexicology, 2021
This article questions the link between creativity, lexical creation and humor in literary texts, more specifically in three of Rikki Ducornet’s novels: The Stain, The Fountains of Neptune and Phosphor in Dreamland.
Elodie Trolé
doaj   +1 more source

Readthrough compounds for nonsense mutations: bridging the translational gap.

open access: yesTrends in Molecular Medicine, 2023
Approximately 10% of all pathological mutations are nonsense mutations that are responsible for several severe genetic diseases for which no treatment regimens are currently available.
S. Spelier   +4 more
semanticscholar   +1 more source

Mening med vrøvlet

open access: yesBarnboken: Tidskrift för Barnlitteraturforskning, 2021
Making Sense of Nonsense: Readings of Children’s Poetry as Play and Creative Thinking Abstract: Nonsense and meaning are not necessarily conflicting concepts, but can be conceived of as a hendiadys, that is, not opposites, the one or the other, but as
Claus K. Madsen, Lea Allouche
doaj   +1 more source

O nonsense de Lewis Carroll

open access: yesPerspectiva Filosófica, 2020
O presente trabalho apresenta uma noção de nonsense própria às obras de Lewis Carroll e elaborada com base em seu próprio arcabouço teórico, seguida de uma análise das relações entre as noções de nonsense de Lewis Carroll e Wittgenstein, concluindo que ...
John Lennon Lindermann
doaj   +1 more source

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