Results 21 to 30 of about 27,331 (253)
Gut and Liver, 2013 Background/AimsWe aimed to investigate the relation-ships among various mutations of the p53 gene and their protein products, histological characteristics, and disease prognosis of primary colorectal cancer in Isfahan, central Iran.Methods : Sixty-one ...
doaj +1 more source
Blah, Blah, Blah: Making Sense of Nonsense in Irish Vocal Music
Musical Offerings, 2014 This paper seeks to provide a foundation for understanding lilting, a traditional type of vocal music found in Ireland that involves improvising non-lexical vocables to dance tunes, in order to help preserve this genre in its traditional form as well as ...
Catherine E. Mullins
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Making (Non)Sense of the Sea, Sand and Self in The Boy in the Bush by D.H. Lawrence and M.L. Skinner
Études Lawrenciennes, 2023 In this paper, I discuss how Lewis Carroll’s Alice narratives, and in particular his so-called nonsense poem “The Walrus and the Carpenter” (from Through the Looking-Glass, 1871), can read as subtexts to the opening chapters of The Boy in the Bush by D.H.
Shirley Bricout
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Acto poético <> Acto psicoanalítico: literatura, retórica y nonsense
Acta Poética, 2017 El psicoanálisis intenta captar el deseo del sujeto “al pie de la letra”: literatura y psicoanálisis comparten el hecho de que se crean nuevos mundos a partir de la palabra.
Norman Marín Calderón
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, 2008 In his Paradoxes (1995: Cambridge University Press: 149) Mark Sainsbury presents the following pair of sentences: Line 1: The sentence written on Line 1 is nonsense. Line 2: The sentence written on Line 1 is nonsense.
Damschen, Gregor
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
PhilosophiesI suggest here ecologies of the nascent state, posing the following general questions: what is this state and what is it to live, to fabricate modes of life, in its immanence?
Filipe Ferreira
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Molecular approaches fighting nonsense [PDF]
, 2021 : Nonsense mutations are the result of single nucleotide substitutions in the DNA that change a sense codon (coding for an amino acid) to a nonsense or premature termination codon (PTC) within the coding region of the mRNA [...]
Ivana Pibiri, Pibiri I.
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FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source