Results 41 to 50 of about 371,135 (330)

An engineered Tetrahymena tRNA(Gln) for in vivo incorporation of unnatural amino acids into proteins by nonsense suppression [PDF]

open access: yes, 1996
A new tRNA, THG73, has been designed and evaluated as a vehicle for incorporating unnatural amino acids site-specifically into proteins expressed in vivo using the stop codon suppression technique.
Abelson, John N.   +7 more
core   +1 more source

Strategies against nonsense: oxadiazoles as translational readthrough-inducing drugs (TRIDs) [PDF]

open access: yes, 2019
This review focuses on the use of oxadiazoles as translational readthrough-inducing drugs (TRIDs) to rescue the functional full-length protein expression in mendelian genetic diseases caused by nonsense mutations.
Campofelice A.   +6 more
core   +1 more source

Stop that nonsense!

open access: yeseLife, 2014
Cells can avoid the effects of so-called ‘nonsense’ mutations by several methods, including a newly discovered mechanism driven by microRNA molecules.
openaire   +4 more sources

Word-decoding as a function of temporal processing in the visual system. [PDF]

open access: yes, 2013
This study explored the relation between visual processing and word-decoding ability in a normal reading population. Forty participants were recruited at Arizona State University.
Holloway, Steven R   +2 more
core   +8 more sources

What is a "Sebastian"?: A nonsensical look at the poetry of Yona Wallach

open access: yesThe European Journal of Humour Research, 2017
This article compares the nonsense works of Lewis Carroll to the poetry of the canonical Hebrew poet Yona Wallach. Both writers present literary works which are not based on the logic of 'ordinary' reality, but rather on systems of unfamiliar, surreal ...
Ailor Porat
doaj   +3 more sources

Theragnosis for Duchenne Muscular Dystrophy

open access: yesFrontiers in Pharmacology, 2021
Dystrophinopathies cover a spectrum of rare progressive X-linked muscle diseases, arising from DMD mutations. They are among the most common pediatric muscular dystrophies, being Duchenne muscular dystrophy (DMD) the most severe form.
Leonela Luce   +12 more
doaj   +1 more source

First-Person Knowledge: Wittgenstein, Cavell, and "Therapy" [PDF]

open access: yes, 2002
The recent publication of The New Wittgenstein signals the arrival of a distinctive "therapeutic" reading of Ludwig Wittgenstein"s philosophical enterprise. As announced in its Preface, this collection presents the "nonsense" of philosophy as the subject
Meyer, Thomas
core  

PAX6 mutations: genotype-phenotype correlations [PDF]

open access: yes, 2005
BACKGROUND: The PAX6 protein is a highly conserved transcriptional regulator that is important for normal ocular and neural development. In humans, heterozygous mutations of the PAX6 gene cause aniridia (absence of the iris) and related developmental eye
Hanson, Isabel M   +2 more
core   +3 more sources

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

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