Results 191 to 200 of about 50,057 (258)

<i>Smg5</i> Enhances Oligodendrocyte Differentiation via Nonsense-Mediated mRNA Decay of <i>Hnrnpl</i> Variant Transcripts. [PDF]

J Neurosci
Jiang M, Li C, Xie B, Li T, Dai ZM, Qiu M.   +5 more
europepmc   +1 more source

A novel frameshift <i>STAG1</i> variant exhibiting haploinsufficiency due to the nonsense-mediated mRNA decay: a case report and literature review. [PDF]

Front Pediatr
Jiang C, Wu K, Zhou Y.
europepmc   +1 more source

Insights From Nonsense-Mediated mRNA Decay for Prognosis in Homologous Recombination-Deficient Ovarian Cancer. [PDF]

Cancer Sci
Han L, Liu J, Zhang R, Cheng Y, Dong L, Wei L, Liu J, Wang K, Yu J.   +8 more
europepmc   +1 more source

A novel homozygous frameshift mutation likely causing nonsense-mediated mRNA decay in an Algerian kindred with CD19 complex deficiency. [PDF]

Front Immunol
Belaid B, Chan KW, Lamara Mahammed L, Leung D, Makhloufi S, Bendaoud F, Sakhri H, Berkani LM, Allam I, Merah F, Baaziz H, Lo B, Rosa Duque JS, Lau YL, Djidjik R.   +14 more
europepmc   +1 more source

Endonucleolytic cleavage is the primary mechanism of decay elicited by <i>C. elegans</i> nonsense-mediated mRNA decay. [PDF]

Genome Res
Viscardi MJ, Sehgal E, Arribere JA.
europepmc   +1 more source

The mechanism of nonsense-mediated mRNA decay

, 2015
Nonsense-mediated mRNA decay (NMD) is a quality control pathway that recognizes and rapidly degrades mRNAs containing a premature termination codon (PTC). The prevalent model, proposes that in mammals a translation termination codon is generally interpreted as premature if it is localized more than 50-55 nucleotides upstream of the last exon-exon ...
openaire   +1 more source

Up-Frameshift Factors from Phytopathogenic Fungi Play a Crucial Role in Nonsense-Mediated mRNA Decay. [PDF]

J Fungi (Basel)
Lu P, Wang J, Wang X, Wang D, Shi H.
europepmc   +1 more source

Functional investigation of the RNA helicase MOV10 with respect to its interplay with factors involved in nonsense-mediated mRNA decay. [PDF]

J Biol Chem
Xue G, Faber GP, Pommerening LS, Mallick M, Gupta A, Wahl MC, Shav-Tal Y, Chakrabarti S.   +7 more
europepmc   +1 more source

Effects of heterozygous SMG1 mutations on nonsense-mediated mRNA decay in human pluripotent stem cell model. [PDF]

Mol Cells
Lee C, Lee JS, Kwon Y, Shin A, Jeong TY, Yang J, Hwang JW, Kim HI, Choi HJ, Kim YK, Choi M, Kim K, Sun W, Chae JH.   +13 more
europepmc   +1 more source

Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors

Cellular and Molecular Life Sciences, 2010
P. Nicholson, H. Yepiskoposyan, S. Metze, Rodolfo Zamudio Orozco, Nicole Kleinschmidt, O. Mühlemann   +5 more
semanticscholar   +1 more source