Results 211 to 220 of about 50,057 (258)

Modulation of UPF1 catalytic activity upon interaction of SARS-CoV-2 Nucleocapsid protein with factors involved in nonsense mediated-mRNA decay. [PDF]

Nucleic Acids Res
Mallick M, Boehm V, Xue G, Blackstone M, Gehring NH, Chakrabarti S.   +5 more
europepmc   +1 more source

A system of reporters for comparative investigation of EJC-independent and EJC-enhanced nonsense-mediated mRNA decay. [PDF]

Nucleic Acids Res
Kolakada D, Campbell AE, Galvis LB, Li Z, Lore M, Jagannathan S.   +5 more
europepmc   +1 more source

Nonsense-mediated mRNA decay of mRNAs encoding a signal peptide occurs primarily after mRNA targeting to the endoplasmic reticulum. [PDF]

Mol Cells
Shin MK, Chang J, Park J, Lee HJ, Woo JS, Kim YK.   +5 more
europepmc   +1 more source

Readthrough Activators and Nonsense-Mediated mRNA Decay Inhibitor Molecules: Real Potential in Many Genetic Diseases Harboring Premature Termination Codons. [PDF]

Pharmaceuticals (Basel)
Benslimane N, Loret C, Chazelas P, Favreau F, Faye PA, Lejeune F, Lia AS.   +6 more
europepmc   +1 more source

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Nonsense-mediated mRNA decay: terminating erroneous gene expression.

Current Opinion in Cell Biology, 2004
Nonsense-mediated mRNA decay is a surveillance pathway that reduces errors in gene expression by eliminating aberrant mRNAs that encode incomplete polypeptides. Recent experiments suggest a working model whereby premature and normal translation termination events are distinct as a consequence of the spatial relationship between the termination codon ...
K. Baker, R. Parker
semanticscholar   +5 more sources

Circular RNAs trigger nonsense-mediated mRNA decay.

Molecular Cell
Circular RNAs (circRNAs) are covalently closed single-stranded RNAs produced predominantly through a back-splicing process. They play regulatory roles in various biological and physiological processes; however, the molecular mechanisms by which circRNAs ...
Sung Ho Boo, Min-Kyung Shin, H. Hwang, Hyeonseo Hwang, Su-Hsin Chang, TaeSoo Kim, Daehyun Baek, Yoon Ki Kim   +7 more
semanticscholar   +3 more sources

Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics

Nature Reviews Molecular Cell Biology, 2004
L. Maquat
semanticscholar   +3 more sources

Nonsense-mediated mRNA decay: an intricate machinery that shapes transcriptomes

Nature Reviews Molecular Cell Biology, 2015
Søren Lykke‐Andersen, T. Jensen
semanticscholar   +3 more sources

Nonsense-mediated mRNA decay (NMD) mechanisms

Nature Structural & Molecular Biology, 2009
Nonsense-mediated mRNA decay (NMD) is a translation-coupled mechanism that eliminates mRNAs containing premature translation-termination codons (PTCs). In mammalian cells, NMD is also linked to pre-mRNA splicing, as in many instances strong mRNA reduction occurs only when the PTC is located upstream of an intron.
S. Brogna, Jikai Wen
semanticscholar   +3 more sources