Results 31 to 40 of about 56,005 (221)

Genetic Determinants of Virulence in Pathogenic Lineage 2 West Nile Virus Strains

Emerging Infectious Diseases, 2008
We determined complete genome sequences of lineage 2 West Nile virus (WNV) strains isolated from patients in South Africa who had mild or severe WNV infections.
Elizabeth M. Botha, Wanda Markotter, Mariaan Wolfaardt, Janusz T. Paweska, Robert Swanepoel, Gustavio Palacios, Louis H. Nel, Marietjie Venter   +7 more
doaj   +1 more source

Modulation of Host Immunity by Human Respiratory Syncytial Virus Virulence Factors: A Synergic Inhibition of Both Innate and Adaptive Immunity [PDF]

, 2017
Indexación: Web of Science; Scopus.The Human Respiratory Syncytial Virus (hRSV) is a major cause of acute lower respiratory tract infections (ARTIs) and high rates of hospitalizations in children and in the elderly worldwide.
Alexis M. Kalergis, Alexis M. Kalergis, Claudia A. Riedel, Emma Rey-Jurado, Gisela Canedo-Marroquín, Juan M. Saavedra, Margarita K. Lay, Margarita K. Lay, Orlando Acevedo-Acevedo, Susan M. Bueno   +9 more
core   +2 more sources

A comprehensive functional map of the hepatitis C virus genome provides a resource for probing viral proteins. [PDF]

, 2014
UnlabelledPairing high-throughput sequencing technologies with high-throughput mutagenesis enables genome-wide investigations of pathogenic organisms. Knowledge of the specific functions of protein domains encoded by the genome of the hepatitis C virus ...
Arumugaswami, Vaithilingaraja, Chen, Shu-Hwa, Chen, Zugen, Chu, Virginia, Lin, Chung-Yen, Lo, Hung-Hao, Olson, C Anders, Qi, Hangfei, Remenyi, Roland, Stokelman, Tamar, Su, Sheng-Yao, Sun, Ren, Truong, Shawna, Wu, Nicholas C, Wu, Ting-Ting   +14 more
core   +2 more sources

Nonstructural Protein-2 and the Replication of Canine Parvovirus

Virology, 1998
The nonstructural protein-2 (NS2) of canine parvovirus (CPV) is produced from the left-hand open reading frame of the viral genome and contains 87 amino-terminal amino acids in common with nonstructural protein 1 (NS1) joined to 78 amino acids from an alternative open reading frame. In the minute virus of mice parvovirus NS2 plays a role in controlling
Wang, Dai, Yuan, Wen, Davis, Ian, Parrish, Colin R.   +3 more
openaire   +2 more sources

Non-structural proteins of arthropod-borne bunyaviruses: roles and functions [PDF]

, 2013
Viruses within the Bunyaviridae family are tri-segmented, negative-stranded RNA viruses. The family includes several emerging and re-emerging viruses of humans, animals and plants, such as Rift Valley fever virus, Crimean-Congo hemorrhagic fever virus ...
Alain Kohl, Anne-Lie Blomström, Delhaye, Dunn, Esther Schnettler, Geerts-Dimitriadou, Hampsey, Isabelle Dietrich, Kakach, Lanciotti, Nagata, Saleh Eifan, Storms, Verbruggen, Wijkamp, Yadani, Ye, Zhao   +17 more
core   +3 more sources

Pestivirus Virion Morphogenesis in the Absence of Uncleaved Nonstructural Protein 2-3 [PDF]

Journal of Virology, 2012
ABSTRACTThe familyFlaviviridaecontains three genera of positive-strand RNA viruses, namely,Flavivirus,Hepacivirus(e.g., hepatitis C virus [HCV]), andPestivirus. Pestiviruses, like bovine viral diarrhea virus (BVDV), bear a striking degree of similarity to HCV concerning polyprotein organization, processing, and function.
E, Lattwein, O, Klemens, S, Schwindt, P, Becher, N, Tautz   +4 more
openaire   +2 more sources

Inhibition of type I interferon induction and signalling by mosquito-borne flaviviruses [PDF]

, 2017
The Flavivirus genus (Flaviviridae family) contains a number of important human pathogens, including dengue and Zika viruses, which have the potential to cause severe disease.
Clark, Jordan J., Cumberworth, Stephanie, Donald, Claire L., Kohl, Alain   +3 more
core   +1 more source

Inhibition of Venezuelan Equine Encephalitis Virus Using Small Interfering RNAs

Viruses, 2022
Acutely infectious new world alphaviruses such as Venezuelan Equine Encephalitis Virus (VEEV) pose important challenges to the human population due to a lack of effective therapeutic intervention strategies.
Amrita Haikerwal, Michael D. Barrera, Nishank Bhalla, Weidong Zhou, Niloufar Boghdeh, Carol Anderson, Farhang Alem, Aarthi Narayanan   +7 more
doaj   +1 more source

The nonstructural protein NSs of Schmallenberg virus is targeted to the nucleolus and induces nucleolar disorganization [PDF]

, 2016
Schmallenberg virus (SBV) was discovered in Germany in late 2011 and then spread rapidly to many European countries. SBV is an orthobunyavirus that causes abortion and congenital abnormalities in ruminants.
Breard, Emmanuel, Caignard, Grégory, Cochet, Marielle, Coulpier, Muriel, Fablet, Aurore, Gouzil, Julie, Kundlacz, Cindy, Lara, Estelle, Palmarini, Massimo, Sailleau, Corinne, Varela, Mariana, Viarouge, Cyril, Vitour, Damien, Zientara, Stéphan   +13 more
core   +3 more sources

Molecular Dissection of Porcine Reproductive and Respiratory Virus Putative Nonstructural Protein 2 [PDF]

, 2006
Arteriviridae in the order Nidovirales. The virus is now known to consist of two different genotypes based on the finding that the prototypes viruses, Lelystad virus (European-like, Type 1) and VR-2332 (North American-like, Type 2), display only approximately 60% nucleotide identity. PRRSV has since been shown to consist of multiple virus isolates that
Faaberg, Kay S., Han, Jun, Wang, Yue
openaire   +2 more sources