Results 21 to 30 of about 10,899 (169)

Nontuberculous Mycobacteria, Macrophages, and Host Innate Immune Response

Infection and Immunity, 2021
Although nontuberculous mycobacteria (NTM) are considered opportunistic infections, incidence and prevalence of NTM infection are increasing worldwide becoming a major public health threat. Innate immunity plays an essential role in mediating the initial
M. Shamaei, M. Mirsaeidi
semanticscholar   +1 more source

T-Cell Exhaustion in Mycobacterium tuberculosis and Nontuberculous Mycobacteria Infection: Pathophysiology and Therapeutic Perspectives

Microorganisms, 2021
Immune exhaustion is a condition associated with chronic infections and cancers, characterized by the inability of antigen-specific T cells to eliminate the cognate antigen. Exhausted T cells display a peculiar phenotypic profile and exclusive functional
A. Lombardi, S. Villa, Valeria Castelli, A. Bandera, A. Gori   +4 more
semanticscholar   +1 more source

The Impact of Nontuberculous Mycobacteria Species on Mortality in Patients With Nontuberculous Mycobacterial Lung Disease

Frontiers in Microbiology, 2022
Patients with nontuberculous mycobacterial lung disease (NTM-LD) have increased mortality. The impact of NTM species on the risk of mortality remains unclear, especially that of death by non-cancer causes.
Ping-Huai Wang, S. Pan, Sudan Wang, C. Shu, Chin-Hao Chang   +4 more
semanticscholar   +1 more source

General Overview of Nontuberculous Mycobacteria Opportunistic Pathogens: Mycobacterium avium and Mycobacterium abscessus

Journal of Clinical Medicine, 2020
Nontuberculous mycobacteria (NTM) are emerging human pathogens, causing a wide range of clinical diseases affecting individuals who are immunocompromised and who have underlying health conditions.
K. To, Ruoqiong Cao, Aram Yegiazaryan, James Owens, V. Venketaraman   +4 more
semanticscholar   +1 more source

Phage Therapy for Nontuberculous Mycobacteria: Challenges and Opportunities

Pulmonary Therapy, 2022
Non-tuberculous mycobacterium (NTM) infections are often clinically challenging, with lengthy antibiotic regimens that fail to resolve the infections with few good outcomes remaining.
G. Hatfull
semanticscholar   +1 more source

In vitro susceptibility patterns for rapidly growing nontuberculous mycobacteria in the United States.

Diagnostic microbiology and infectious disease, 2022
Antimicrobial susceptibility testing for rapidly growing mycobacteria (RGM) is uncommon or only performed in large reference laboratories. Here we developed a cumulative antibiogram for 14 RGM using the largest sample size to date (N = 3860).
J. Hunkins, Vinicius-C-N de-Moura, J. Eddy, C. Daley, Reeti Khare   +4 more
semanticscholar   +1 more source

The respiratory microbiome and nontuberculous mycobacteria: an emerging concern in human health

European Respiratory Review, 2021
Nontuberculous mycobacteria (NTM) are diverse microbial species encompassing commensals and pathogens with the ability to cause pulmonary disease in both immunocompetent and immunocompromised individuals.
Christina S. Thornton, Madeline Mellett, J. Jarand, Leila Barss, S. Field, D. Fisher   +5 more
semanticscholar   +1 more source

Distinguishing nontuberculous mycobacteria from Mycobacterium tuberculosis lung disease from CT images using a deep learning framework

European Journal of Nuclear Medicine and Molecular Imaging, 2021
To develop and evaluate the effectiveness of a deep learning framework (3D-ResNet) based on CT images to distinguish nontuberculous mycobacterium lung disease (NTM-LD) from Mycobacterium tuberculosis lung disease (MTB-LD). Chest CT images of 301 with NTM-
Li Wang, Wenlong Ding, Y. Mo, Dejun Shi, Shuo Zhang, Lingshan Zhong, Kai Wang, Jigang Wang, Chencui Huang, Shu Zhang, Z. Ye, Jun Shen, Z. Xing   +12 more
semanticscholar   +1 more source

Nontuberculous Mycobacteria in Humans, Animals, and Water in Zambia: A Systematic Review

Frontiers in Tropical Diseases, 2021
Nontuberculous mycobacteria (NTM) are environmental opportunistic pathogens of humans and animals that are emerging with a serious public health impact particularly in individuals with Acquired Immunodeficiency Syndromes.
M. Zulu, Ngula Monde, P. Nkhoma, Sydney Malama, Musso Munyeme   +4 more
semanticscholar   +1 more source

Increasing Trend of Nontuberculous Mycobacteria Isolation in a Referral Clinical Laboratory in South Korea

Medicina, 2021
Background and Objectives: Nontuberculous mycobacteria (NTM) infections are increasing worldwide. We evaluated the annual trends of NTM isolation on acid-fast bacillus (AFB) culture, compared to that of Mycobacterium tuberculosis, and the distribution of
Yu-Mi Lee, Minjung Kim, Young-Jin Kim
semanticscholar   +1 more source