Results 111 to 120 of about 196 (129)

Impairment of Learning and Memory after Photothrombosis of the Prefrontal Cortex in Rat Brain: Effects of Noopept

Bulletin of Experimental Biology and Medicine, 2002
Experiments were performed on rats trained conditioned passive avoidance response. Acquisition and retention of memory traces were impaired after photothrombosis of the prefrontal cortex. The acyl-prolyl-containing dipeptide Noopept facilitated retention and retrieval of a conditioned passive avoidance response, normalized learning capacity in animals ...
G A, Romanova, F M, Shakova, T A, Gudasheva, R U, Ostrovskaya   +3 more
openaire   +2 more sources

[Noopept in the treatment of mild cognitive impairment in patients with stroke].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2012
Noopept is a neuroprotector and nootropics. Literature data revealed the treatment effect of noopept on mild cognitive impairment in patients with discirculatory encephalopathy. The present open prospective study included 60 patients with stroke treated with noopept during 12 months.
A V, Amelin, A Iu, Iliukhina, A A, Shmonin   +2 more
openaire   +1 more source

The Effect of Noopept on Neurochemical Changes in the Retina during the Experimental Thrombosis of Its Vessels

Neurochemical Journal, 2019
We studied the effect of the neuroprotective dipeptide drug noopept on the level of biogenic amines in the retina during the thrombosis of its vessels in experiments with male chinchilla rabbits. Ischemic lesion of the retina was modeled by intravenous administration of rose bengal at a dose of 40 mg/kg body weight followed by 10-min transpupillary ...
A. V. Kolesnikov, A. V. Shchul’kin, O. I. Barenina, E. N. Yakusheva, V. S. Kudrin, R. U. Ostrovskaya, M. G. Uzbekov, M. M. Shishkin   +7 more
openaire   +1 more source

[Behavior of mice from different strains: modifications produced by noopept].

Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova, 2008
Genotype-dependent behavioral effects were demonstrated in BALB/c, C57BL/6J [Russian character: see text] DBA/2J mice after injections of nootropic drug Noopept. In an elevated plus maze, drug administration induced an increase in the number of enterings into bright arms in BALB/c mice, whereas the opposite effect was observed in C57BL/6J.
A P, Bel'nik, R U, Ostrovskaia, I I, Poletaeva   +2 more
openaire   +1 more source

[Genotype-dependent mice behavior in cognitive tasks. Effect of noopept].

Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova, 2008
The interstrain differences in performance of C57BL/6J, BALB/c and DBA/2J male mice in two cognitive tasks were found. Mice C57BL/6J showed good learning ability and preservation of memory traces tested 10 days after performance in a simplified version of Morris water maze.
A P, Bel'nik, R U, Ostrovskaia, I I, Poletaeva   +2 more
openaire   +1 more source

[Prevention of neuro- and cardiotoxic side effects of tuberculosis chemotherapy with noopept].

Klinicheskaia meditsina, 2009
The study evaluated clinical efficiency of noopept used to prevent adverse side effects of antituberculous agents. It included 60 patients with newly diagnosed respiratory tuberculosis. Those in group 1 (n = 30) received 10 mg of noopept twice daily during the first month. The treatment promoted functional normalization of vegetative nervous system and
A V, Mordyk, A V, Lysov, A V, Kondria, M A, Gol'dzon, N V, Khlebova   +4 more
openaire   +1 more source

Correction of alcohol-induced disorders of working memory with noopept

Molekulyarnaya Meditsina (Molecular medicine), 2022
Larisa Gennadievna Kolik, Vasiliy Grigorievich Konkov, Alexandra Valrr’yanovna Sorokina, Irina Alexsandrovna Miroshkina, Kirill Alekseevich Kasabov, Vladimir Sergeevich Kudrin, Andrey Dmitrievich Durnev   +6 more
openaire   +1 more source

[Anti-inflammatory properties of noopept (dipeptide nootropic agent GVS-111)].

Eksperimental'naia i klinicheskaia farmakologiia, 2002
It is established that single intravenous (0.5 and 5 mg/kg, p.o.) or single peroral (10, 50, 100 mg/kg) and prolonged peroral (5 mg/kg, over 10 days) administration of noopept produces a dose-dependent inhibition of the model inflammatory response to concanavaline A in CBA mice.
L P, Kovalenko, M G, Miramedova, S V, Alekseeva, T A, Gudasheva, R U, Ostrovskaia, S B, Seredenin   +5 more
openaire   +1 more source

Bioaccessibility of the new dipeptide nootropic drug noopept

Pharmaceutical Chemistry Journal, 2004
S. S. Boiko, V. P. Zherdev, T. A. Gudasheva, R. U. Ostrovskaya, S. A. Korotkov, O. Yu. Kravtsova   +5 more
openaire   +1 more source

P.5.039 Experimental and clinicalpharmacokinetics of noopept

European Neuropsychopharmacology, 2005
openaire   +1 more source