Results 191 to 200 of about 3,775 (250)

TREATMENT OF RAYNAUD SYNDROMES WITH PIRACETAM(NOOTROPIL R),NOOTROPIC AND ANIPLATELET AGENT

Thrombosis and Haemostasis, 1987
Three prospective studies have been performed with piracetam (Nootropil ®-) in the treatment of Raynaud disease and syndromes.The first one, realized in 20 cases of Raynaud disease established that 8 g piracetam daily was the optimal dosage necessary to obtain a significant clinical, ultrasonic and biologic improvement.In the second one, 58 cases of ...
M Moriau, E Lavenne-Pardonge, C H Col-De Beys   +2 more
openaire   +1 more source

Synthesis of the benzenoid analogue of the chinese nootropic agent huperzine a

Tetrahedron Letters, 1989
Abstract A short synthesis of the benzene isostere of huperzine A, an anticholinesterase of potential use in the treatment of Alzheimer's disease, is described starting from β-tetralone.
Yan Xia, E.Rajarathnam Reddy, Alan P. Kozikowski   +2 more
openaire   +1 more source

[Facilitation of evoked transcallosal responses by nootropic agents].

Biomedica biochimica acta, 1985
The effect of nootropic drugs was investigated by studying their influences on transcallosal responses in rats. Piracetam, meclofenoxate, vinpocetin, pyritinol, orotic acid and dihydroergotoxine as well as its components dihydroergocornine and dihydroergocrytpine enhance in a dose dependent manner the amplitudes of transcallosal responses.
U, Kirsch, J, Schmidt
openaire   +1 more source

Antidepressant activities of WEB 1881, a new nootropic agent.

Polish journal of pharmacology and pharmacy, 1990
The central action, particularly potential antidepressant activity of WEB 1881, a new nootropic drug related to piracetam, was investigated in rats and mice. WEB 1881 antagonizes the reserpine- and apomorphine-induced hypothermia, potentiates the behavioral effect of DOPA and dihydroxyphenylserine, as well as the TRH-induced hyperthermia. Piracetam was
J, Maj, Z, Rogóz, G, Skuza, H, Sowińska, G, Nowak   +4 more
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X‐Ray, NMR, and Theoretical Studies of the Nootropic Agent BMY‐21502, a Pyrrolidinone Derivative

Journal of Pharmaceutical Sciences, 1994
The preferred crystalline, solution, and in vacuo arrangements of 1-[[1-[2-trifluoromethyl)-4-pyrimidinyl]-4-piperidinyl]methyl]-2-pyrroli dinone (BMY-21502) were investigated by means of single-crystal X-ray diffraction, 1H and 13C NMR spectroscopy, and semiempirical molecular orbital and molecular mechanics calculations.
BANDOLI, GIULIANO, DOLMELLA, ALESSANDRO, NICOLINI, MARINO, F. Tisato   +3 more
openaire   +5 more sources

Meta-analysis: the efficacy of nootropic agent Cerebrolysin in the treatment of Alzheimer’s disease

Journal of Neural Transmission, 2007
To determine the therapeutic effect of nootropic agent Cerebrolysin on patients with mild to moderate Alzheimer's disease (AD), we searched the Cochrane Library, Medline, PubMed, and Chinese Biomedical Literature Analysis and Retrieval System for Compact Disc (CBMDISC), and communicated with EBEWE Pharmaceutical Ltd, for randomized trials comparing ...
Z-H, Wei, Q-B, He, H, Wang, B-H, Su, H-Z, Chen   +4 more
openaire   +2 more sources

Memory effects of the combination of medazepam with nootropic agents.

Acta physiologica et pharmacologica Bulgarica, 1989
Experiments were made on rats using step-through passive avoidance method to study the effect of the benzodiazepine medazepam (Mz) on the retention of the memory traces during tests on the 3rd hour, 24th hour and 7th day after training, as well as the influencing of this effect by the nootropic agents meclofenoxate (Mf), aniracetam (Anc) and Euclidan ...
S, Rousseva, V V, Petkov, V D, Petkov, T A, Voronina, L N, Nerobkova, I A, Ivanova, V, Stoyanova   +6 more
openaire   +1 more source

[Anti-inflammatory properties of noopept (dipeptide nootropic agent GVS-111)].

Eksperimental'naia i klinicheskaia farmakologiia, 2002
It is established that single intravenous (0.5 and 5 mg/kg, p.o.) or single peroral (10, 50, 100 mg/kg) and prolonged peroral (5 mg/kg, over 10 days) administration of noopept produces a dose-dependent inhibition of the model inflammatory response to concanavaline A in CBA mice.
L P, Kovalenko, M G, Miramedova, S V, Alekseeva, T A, Gudasheva, R U, Ostrovskaia, S B, Seredenin   +5 more
openaire   +1 more source

[Effect of nootropic agents on serum biochemical indices in intellectually deficient children].

Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1984
It was shown that a marked therapeutic effect or its absence in the piracetam and nootropil treatment of children with different degrees of mental retardation is largely determined by the presence in patients' metabolism (before treatment) of certain combined changes in the general activity of lactate dehydrogenase (LDH) and its isoenzymic spectrum ...
N F, Turova, L A, Ermolina, V A, Baryshnikov, R A, Kopaladze, A V, Aziavchik   +4 more
openaire   +1 more source

EFFECT OF NOOTROPIC AGENTS ON BRAIN CHOLINERGIC MECHANISMS

Clinical Neuropharmacology, 1984
PEDATA, FELICITA, MORONI, FLAVIO, PEPEU, GIANCARLO   +2 more
openaire   +2 more sources