Results 171 to 180 of about 2,327 (198)

X‐Ray, NMR, and Theoretical Studies of the Nootropic Agent BMY‐21502, a Pyrrolidinone Derivative

Journal of Pharmaceutical Sciences, 1994
The preferred crystalline, solution, and in vacuo arrangements of 1-[[1-[2-trifluoromethyl)-4-pyrimidinyl]-4-piperidinyl]methyl]-2-pyrroli dinone (BMY-21502) were investigated by means of single-crystal X-ray diffraction, 1H and 13C NMR spectroscopy, and semiempirical molecular orbital and molecular mechanics calculations.
BANDOLI, GIULIANO, DOLMELLA, ALESSANDRO, NICOLINI, MARINO, F. Tisato   +3 more
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ChemInform Abstract: Synthesis of the Benzenoid Analogue of the Chinese Nootropic Agent Huperzine A.

ChemInform, 1990
AbstractThe benzoid analogue (XIV) of the alkaloid huperzine A (XV) is prepared as outlined in the reaction scheme.
Y. XIA, E. R. REEDY, A. P. KOZIKOWSKI
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[Modern problems of the pharmacology of nootropic agents: the status and outlook].

Farmakologiia i toksikologiia, 1991
The information about the current state and perspectives of research in the field of development and study of the mechanisms of action of nootropic drugs is presented. The methodology of experimental study of nootropics is covered which is based on modelling different disorders of the integrative activity of the brain including old animals.
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[Nootropic agents in the complex treatment of patients with traumatic epilepsy].

Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1990
A study was made of the therapeutic efficacy of nootropic agents in multimodality treatment of 62 patients with traumatic epilepsy. The treatment efficacy was appraised with regard to the time-course of changes in psychopathological symptomatology. The data obtained have been processed statistically according to criteria for the signs.
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Synthesis, docking, and biological evaluation of novel 1-benzyl-4-(4-(R)-5-sulfonylidene-4,5-dihydro-1H-1,2,4-triazol-3-yl)pyrrolidin-2-ones as potential nootropic agents

European Journal of Medicinal Chemistry, 2022
Marharyta Suleiman, Andrii I Fedosov, Sergiy M Kovalenko   +2 more
exaly  

[Effect of nootropic agents on serum biochemical indices in intellectually deficient children].

Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1984
It was shown that a marked therapeutic effect or its absence in the piracetam and nootropil treatment of children with different degrees of mental retardation is largely determined by the presence in patients' metabolism (before treatment) of certain combined changes in the general activity of lactate dehydrogenase (LDH) and its isoenzymic spectrum ...
N F, Turova, L A, Ermolina, V A, Baryshnikov, R A, Kopaladze, A V, Aziavchik   +4 more
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Nootropic agents reviewed

Inpharma Weekly, 2001
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ZINC - A TRACE-ELEMENT AS A NOOTROPIC AGENT

Clinical Neuropharmacology, 1992
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Pharmacological studies on bacopa monniera, an Ayurvedic nootropic agent

European Neuropsychopharmacology, 1996
B.N. Dhawan, H.K. Singh
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[Hypoxia and memory. Specific features of nootropic agents effects and their use].

Vestnik Rossiiskoi akademii meditsinskikh nauk, 2000
Hypoxia and hypoxic adaptation are powerful factors of controlling memory and behavior processes. Acute hypoxia exerts a differential impact on different deficits of mnestic and cognitive functions. Instrumental reflexes of active and passive avoidance, negative learning, behavior with a change in the stereotype of learning are more greatly damaged ...
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