Results 151 to 160 of about 2,327 (198)

Pyrimidine thioethers: A novel class of antidepressant agents, endowed with anxiolytic, performance enhancing and nootropic activity

European Journal of Medicinal Chemistry, 2023
A series of new pyrimidine thioethers, recognized as the key intermediates in the synthesis of S-DABO antivirals, were prepared and evaluated both in vivo and in silico.
Denis V Kurkin
exaly   +2 more sources

Synthesis and biological evaluation of Schiff’s bases and 2-azetidinones of isonocotinyl hydrazone as potential antidepressant and nootropic agents

Arabian Journal of Chemistry, 2016
The synthesis and pharmacological activity of N′-[(1Z)-(substituted aromatic) methylidene] pyridine-4-carbohydrazides (3a–k) and N-[3-chloro-2-(substituted aromatic)-4-oxoazetidin-1-yl]pyridine-4-carboxamides (5a–k) are described.
Rabindra K Nanda
exaly   +2 more sources

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Nootropic agents

Side Effects of Drugs Annual
K Dean Gubler
exaly   +2 more sources

EFFECT OF NOOTROPIC AGENTS ON BRAIN CHOLINERGIC MECHANISMS

Clinical Neuropharmacology, 1984
Flavio Moroni
exaly   +3 more sources

[The original novel nootropic and neuroprotective agent noopept].

Eksperimental'naia i klinicheskaia farmakologiia, 2003
The paper describes pharmacological properties of the new nootropic drug noopept created using an original approach based on the imitation of a nonpeptide nootrope structure by means of the short-peptide design. In particular, the structure of pyracetam was designed using dipeptide nootropes.
R U, Ostrovskaia, T A, Gudasheva, T A, Voronina, S B, Seredenin   +3 more
openaire   +2 more sources

Synthesis of the benzenoid analogue of the chinese nootropic agent huperzine a

Tetrahedron Letters, 1989
Abstract A short synthesis of the benzene isostere of huperzine A, an anticholinesterase of potential use in the treatment of Alzheimer's disease, is described starting from β-tetralone.
Yan Xia, E.Rajarathnam Reddy, Alan P. Kozikowski   +2 more
openaire   +1 more source

Platelet-activating factor: A new target site for the development of nootropic agents

Drugs of the Future, 2001
null Singh, M., null Saraf, M.K.
openaire   +2 more sources

Investigations on the binding properties of the nootropic agent pyroglutamic acid.

Drugs under experimental and clinical research, 1990
The two stereoisomers of pyroglutamic acid (PCA), a nootropic or cognition-enhancing agent, and classic reference compounds were investigated for their ability to interact with 27 neurotransmitter receptors and drug binding sites prepared from selected areas of the central nervous system and labelled with high affinity and selectivity with specific ...
D, Barone, G, Spignoli
openaire   +2 more sources

Substituted piperazines as nootropic agents: 2- or 3-phenyl derivatives structurally related to the cognition-enhancer DM235

Bioorganic and Medicinal Chemistry Letters, 2015
Luca Guandalini, Maria Vittoria Martino, Lorenzo Di Cesare Mannelli   +2 more
exaly   +2 more sources

Meta-analysis: the efficacy of nootropic agent Cerebrolysin in the treatment of Alzheimer’s disease

Journal of Neural Transmission, 2007
To determine the therapeutic effect of nootropic agent Cerebrolysin on patients with mild to moderate Alzheimer's disease (AD), we searched the Cochrane Library, Medline, PubMed, and Chinese Biomedical Literature Analysis and Retrieval System for Compact Disc (CBMDISC), and communicated with EBEWE Pharmaceutical Ltd, for randomized trials comparing ...
Z-H, Wei, Q-B, He, H, Wang, B-H, Su, H-Z, Chen   +4 more
openaire   +2 more sources