Results 131 to 140 of about 2,221 (171)
Some of the next articles are maybe not open access.
[Analytic evaluation of potential nootropic agents].
Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 2004The paper deals with analytical evaluation of newly prepared substances, derivatives of N-(4-alkoxy-phenyl)-2-(2-oxo-azepan-1-yl)-acetamide. The substances are a homological series (methyl- to hexyl-). The purity of the substances was verified by thin-layer adsorption chromatography, and the principal physical characteristics--melting point and ...
R, Opatrilová, P, Sokolová
openaire +1 more source
[Molecular-biochemical mechanisms of the effects of nootropic agents].
Biulleten' eksperimental'noi biologii i meditsiny, 1990It is a known fact that prophylactic hypodermic injection of non-typical lithonite tranquillizer in the day's dose of 30 mg/kg during 10 days prevents the exhaustion of antioxidant system of the body, normalizes qualitative and quantitative correlation of separate fractions of phospholipids, stabilizes the permeability of erythrocytic membranes and ...
V I, Kresiun, Ia V, Rozhkovskiĭ
openaire +1 more source
Memory effects of the combination of medazepam with nootropic agents.
Acta physiologica et pharmacologica Bulgarica, 1989Experiments were made on rats using step-through passive avoidance method to study the effect of the benzodiazepine medazepam (Mz) on the retention of the memory traces during tests on the 3rd hour, 24th hour and 7th day after training, as well as the influencing of this effect by the nootropic agents meclofenoxate (Mf), aniracetam (Anc) and Euclidan ...
S, Rousseva +6 more
openaire +1 more source
[Facilitation of evoked transcallosal responses by nootropic agents].
Biomedica biochimica acta, 1985The effect of nootropic drugs was investigated by studying their influences on transcallosal responses in rats. Piracetam, meclofenoxate, vinpocetin, pyritinol, orotic acid and dihydroergotoxine as well as its components dihydroergocornine and dihydroergocrytpine enhance in a dose dependent manner the amplitudes of transcallosal responses.
U, Kirsch, J, Schmidt
openaire +1 more source
[Effect of nootropic agents on impulse activity of cerebral cortex neurons].
Eksperimental'naia i klinicheskaia farmakologiia, 2002The effect of nootropes (semax, mexidol, and GVS-111) on the activity of individual neurons in various cerebral cortex regions was studied by microelectrode and microionophoresis techniques in cats immobilized by myorelaxants. It was established that the inhibiting effect of mexidol upon neurons in more than half of cases is prevented or significantly ...
V V, Iasnetsov +6 more
openaire +2 more sources
Antidepressant activities of WEB 1881, a new nootropic agent.
Polish journal of pharmacology and pharmacy, 1990The central action, particularly potential antidepressant activity of WEB 1881, a new nootropic drug related to piracetam, was investigated in rats and mice. WEB 1881 antagonizes the reserpine- and apomorphine-induced hypothermia, potentiates the behavioral effect of DOPA and dihydroxyphenylserine, as well as the TRH-induced hyperthermia. Piracetam was
J, Maj +4 more
openaire +1 more source
[Modern problems of the pharmacology of nootropic agents: the status and outlook].
Farmakologiia i toksikologiia, 1991The information about the current state and perspectives of research in the field of development and study of the mechanisms of action of nootropic drugs is presented. The methodology of experimental study of nootropics is covered which is based on modelling different disorders of the integrative activity of the brain including old animals.
openaire +1 more source
[Nootropic agents in the complex treatment of patients with traumatic epilepsy].
Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1990A study was made of the therapeutic efficacy of nootropic agents in multimodality treatment of 62 patients with traumatic epilepsy. The treatment efficacy was appraised with regard to the time-course of changes in psychopathological symptomatology. The data obtained have been processed statistically according to criteria for the signs.
openaire +1 more source