Results 41 to 50 of about 5,409,842 (383)

Proton-coupled transport mechanism of the efflux pump NorA

open access: yesNature Communications
Efflux pump antiporters confer drug resistance to bacteria by coupling proton import with the expulsion of antibiotics from the cytoplasm. Despite efforts there remains a lack of understanding as to how acid/base chemistry drives drug efflux.
Jianping Li   +7 more
semanticscholar   +1 more source

Expression of norA, norB and norC efflux pump genes mediating fluoroquinolones resistance in MRSA isolates.

open access: yesJournal of Infection in Developing Countries
INTRODUCTION Although fluoroquinolones are used to treat methicillin-resistant Staphylococcus aureus (MRSA)-induced infections, acquisition of antibiotic resistance by bacteria has impaired their clinical relevance.
A. Hamady   +5 more
semanticscholar   +1 more source

Class/Schedule [PDF]

open access: yes, 2012
Postcard from Nora Burnfield, during the Linfield College Semester Abroad Program at Telemark University in Bø ...
Burnfield, Nora
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Memory, Deconstructed and Reconstructed An Ontward Expression of an Inward Reality [PDF]

open access: yes, 2013
Opening Paragraph Lieux de Memoire, or places of memory, are symbolic sites of national identity. Defined in Le Grand Robert de la langue franfaise, the term is attributed to French historian Pierre Nora. Nora has compiled two large project anthologies
Rochford, Jessica
core   +1 more source

Benthic diatoms and some environmental conditions in three lowland streams [PDF]

open access: yes, 2002
This article reports on the ecological preferences of benthic diatoms in relation to pH, conductivity and organic pollution-eutrophication and their tolerance spectrums. Three Pampean streams subjected to different human impacts were studied.
Gomez, Nora, Licursi, Magdalena
core   +2 more sources

Thymoquinone’ potent impairment of multidrug-resistant Staphylococcus aureus NorA efflux pump activity

open access: yesScientific Reports
The drug efflux pump is a crucial mechanism implicated in resistance to multiple antimicrobials. Thymoquinone (TQ) has evidently demonstrated multiple activities, antibacterial being the most effective.
A. A. M. Ahmad   +5 more
semanticscholar   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

First presentation of a Nora-lesion of the talus in a paraossal fasciitis

open access: yesOrthopedic Reviews, 2019
Nora-Lesion is a proliferation that normally develops out of an intact corticalis. The entity of this fibroostotic pseudotumor, as discussed in literature, is triggered from repeating trauma or reactive periosteitis.
Philipp Rottler   +3 more
doaj   +1 more source

The Effect of Thyme (Thymus vulgaris) Extract on the Expression of norA Efflux Pump Gene in Clinical Strains of Staphylococcus aureus [PDF]

open access: yesJournal of Genetic Resources, 2018
The NorA efflux pump considered as one of the contributors to antibiotic resistance in Staphylococcus aureus strains. One of the challenges of the researchers is finding natural plant compounds with the ability to inhibit the pumps. The aim of this study
Ali Salehzadeh   +3 more
doaj   +1 more source

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