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Noradrenaline and neophobia

Physiology & Behavior, 1978
Abstract Lesions of the ascending noradrenergic bundles using the selective neurotoxin 6-hydroxydopamine increased neophobia to a number of novel tastes in rats. These lesions also increased some, but not all, measures of neophobia in novel environments.
S T, Mason, D C, Roberts, H C, Fibiger
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Noradrenaline depletion increases noradrenaline-induced antinociception in mice

Neuroscience Letters, 1985
Mice were treated with N-2-chloroethyl-N-ethyl-2-bromobenzylamine hydrochloride (DSP4), which causes severe noradrenaline (NA) depletions in brain regions and the spinal cord, or vehicle i.p. They were tested 14 days later for antinociception induced by intrathecal injections of different doses of NA.
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