Results 231 to 240 of about 62,748 (289)
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Noradrenergic influences on catalepsy
Psychopharmacology, 1978Widespread depletion of forebrain noradrenaline, produced by the intracerebral injection of 4 microgram of 6-hydroxydopamine into the fibres of the dorsal noradrenergic bundle, potentiated the catalepsy induced by 20 mg/kg of morphine and severely attenuated the catalepsy induced by two separate cholinergic agonists, arecoline and pilocarpine.
S T, Mason, D C, Roberts, H C, Fibiger
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Progress in Neurobiology, 2006
Norepinephrine is involved in intrinsic control of pain. Main sources of norepinephrine are sympathetic nerves peripherally and noradrenergic brainstem nuclei A1-A7 centrally. Peripheral norepinephrine has little influence on pain in healthy tissues, whereas in injured tissues it has variable effects, including aggravation of pain.
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Norepinephrine is involved in intrinsic control of pain. Main sources of norepinephrine are sympathetic nerves peripherally and noradrenergic brainstem nuclei A1-A7 centrally. Peripheral norepinephrine has little influence on pain in healthy tissues, whereas in injured tissues it has variable effects, including aggravation of pain.
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The regulation of the noradrenergic neuron
Journal of Psychiatric Research, 1974Publisher Summary This chapter discusses the regulation of the noradrenergic neuron. A number of regulatory processes exist that influence the biosynthesis of catecholamines in adrenergic neurons. The large number of events, occurring in a highly synchronized fashion, implies a wide variety of possible regulatory sites.
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Noradrenergic and adrenergic functioning in autism
Biological Psychiatry, 1994A neurochemical assessment of noradrenergic and adrenergic functioning was carried out with autistic patients and normal control individuals. Norepinephrine and related compounds were measured in autistic (n = 17 unmedicated, 23 medicated; age range 9-29 years old) and normal controls (n = 27; age range 9-36 years old).
Minderaa, R.B. +4 more
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Possible Noradrenergic Dysfunction in Schizophrenia
Brain Research Bulletin, 1994In spite of extensive studies over the last 2 decades to find direct evidence in support of the dopamine hypothesis of schizophrenia, no undisputed experimental data has been obtained. In contrast, estimation of noradrenalin (another major catecholamine) and its metabolites in postmortem brain and in the cerebrospinal fluid appears to be producing ...
K, Yamamoto +4 more
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Noradrenergic mechanisms in the prefrontal cortex
Journal of Psychopharmacology, 1997There is growing evidence that noradrenergic inputs to the prefrontal cortex (PFC) play an important role in regulating its function. This paper reviews the pharmacological control of noradrenaline (NA) release in this region, with particular reference to our studies using brain microdialysis, and also describes how NA levels are modulated by ...
D J, Nutt +3 more
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The noradrenergic subtype of Parkinson disease: from animal models to clinical practice
Nature Reviews Neurology, 2023K. Ray Chaudhuri +4 more
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Development of the noradrenergic innervation of neocortex
Brain Research, 1979The development of the noradrenaline (NA)-neuron innervation of rat neocortex was studied by fluorescence histochemistry, high affinity uptake of [3H-]NA, and biochemical assay of regional NA content. Fluorescence histochemistry indicates that NA axons enter areas of developing neocortex prenatally and the innervation matures rapidly during early ...
P, Levitt, R Y, Moore
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Genetic Manipulation of Noradrenergic Neurons
The Journal of Pharmacology and Experimental Therapeutics, 2002The neurotransmitter norepinephrine has been the focus of intense investigation for nearly a century. With advances in technology come novel approaches for testing hypotheses about the physiological roles of norepinephrine and the genes involved in norepinephrine (NE) biosynthesis, metabolism, and noradrenergic signaling.
Robert P, Carson, David, Robertson
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The effect of clorgyline on noradrenergic function
Psychopharmacology, 1985A low dosage of the specific MAO-A inhibitor clorgyline (5-10 mg/day) was administered chronically to 10 depressed patients. Peripheral noradrenergic activity, as assessed by measurements of the plasma norepinephrine (NE) concentration, heart rate, and blood pressure, was determined before and after drug treatment. The administration of a low dosage of
R J, Ross +7 more
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