Results 211 to 220 of about 131,387 (308)
Abstract Background Individual variability in clinical response to dopamine replacement therapy (DRT) is a key barrier to efficacious treatment for patients with Parkinson's disease (PD). A better understanding of the neurobiological sources of such interindividual differences is necessary to personalize DRT prescribing, inform future clinical ...
Alex I. Wiesman+5 more
wiley +1 more source
Machine Learning Tool for New Selective Serotonin and Serotonin-Norepinephrine Reuptake Inhibitors. [PDF]
Łapińska N+3 more
europepmc +1 more source
Light‐Activated Pharmacological Tools for Exploring the Cholinergic System
ABSTRACT Cholinergic transmission plays a critical role in both the central and peripheral nervous systems, affecting processes such as learning, memory, and inflammation. Conventional cholinergic drugs generally suffer from poor selectivity and temporal precision, leading to undesired effects and limited therapeutic efficacy. Photopharmacology aims to
Alessio Colleoni+5 more
wiley +1 more source
Innovative therapeutic strategies using ADHD medications tailored to the behavioral characteristics of patients with chronic pain. [PDF]
Kasahara S+5 more
europepmc +1 more source
Adrenal epinephrine and norepinephrine content following denervation and barbiturates [PDF]
Daniel M. Silver+2 more
openalex +1 more source
Recent Developments in the Optical Control of Adrenergic Signaling
ABSTRACT Adrenoceptors (ARs) play a vital role in various physiological processes and are key therapeutic targets. The advent of optical control techniques, including optogenetics and photopharmacology, offers the potential to modulate AR signaling with precise temporal and spatial resolution. In this review, we summarize the latest advancements in the
Shuang Shi+4 more
wiley +1 more source
Editorial: Neurotransmitters and Emotions
Fushun Wang+5 more
doaj +1 more source
Epinephrine vs Norepinephrine as Initial Treatment in Children With Septic Shock.
Eisenberg MA+4 more
europepmc +1 more source