Results 91 to 100 of about 529,333 (248)
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
General Principles Concerning Aggregates of Juridic Persons in the Canonical Legal Order
Kościół i Prawo, 2014 The author of the presented article focused his attention on the issue of principal rules concerning aggregates of juridic persons in the canonical legal order.
Ginter Dzierżon
doaj
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Robust and minimum norm pole assignment with periodic state feedback [PDF]
, 1998 A computational approach is proposed to solve the minimum norm and/or robust pole assignment problem for linear periodic discrete-time systems. The proposed approach uses a periodic Sylvester equation based parametrization of the periodic pole ...
Varga, A.
core
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Discord in Congress: A Discussion with Congressional Expert Norm Ornstein
, 2015 The specter of government shutdown and default on America’s debts is becoming a routine feature of Washington politics. One of the country’s best known experts on Congress – Norm Ornstein – returns to Minnesota to dissect the latest twists and turns in ...
Ornstein, Norm
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Engineering Science and Technology, an International JournalThis study investigates the surface improvement of Direct Metal Laser Sintering (DMLS) produced AlSi10Mg alloy using Abrasive Flow Machining (AFM).
Mehmet Ali Akeloglu +2 more
doaj +1 more source