Results 61 to 70 of about 6,174,260 (271)
RisksIn the insurance literature, accurately predicting extreme losses has been a persistent and important problem. Recently, under the modelling framework of weighted distributions, several finite-mixture size-biased distributions, including size-biased ...
Taehan Bae, Jieun Kim, Jae Youn Ahn
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Studies in Logic, Grammar and Rhetoric, 2023 The development of medicine is based on reliable medical research. This is a process that must be planned in detail and performed in accordance with the accepted study protocol, as any negligence – even a small one – or deviation from the protocol may ...
Milewski Robert, Roszak Magdalena
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Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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This Is Not a Myeloproliferative Neoplasm…
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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Mathematics, 2019 This paper considers sequentially two main problems. First, we estimate both the mean and the variance of the normal distribution under a unified one decision framework using Hall’s three-stage procedure. We consider a minimum risk point estimation
Ali Yousef, Hosny Hamdy
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Evaluating the Normal Distribution [PDF]
This article provides a little table-free C function that evaluates the normal distribution with absolute error less than 8 x 10 ^-16 . A small extension provides relative error near the limit available in double precision: 14 to 16 digits, the limits ...
George Marsaglia
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