Results 71 to 80 of about 2,404,671 (311)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A Property of the Normal Distribution

open access: yesThe Annals of Mathematical Statistics, 1954
The following theorem is proved. Let $X_1, X_2, \cdots, X_n$ be $n$ independently (but not necessarily identically) distributed random variables, and assume that the $n$th moment of each $X_i(i = 1, 2, \cdots, n)$ exists. The necessary and sufficient conditions for the existence of two statistically independent linear forms $Y_1 = \sum^n_{s=1} a_sX_s ...
Lukacs, Eugene, King, Edgar P.
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A Locally Adaptive Normal Distribution [PDF]

open access: yes, 2016
The multivariate normal density is a monotonic function of the distance to the mean, and its ellipsoidal shape is due to the underlying Euclidean metric. We suggest to replace this metric with a locally adaptive, smoothly changing (Riemannian) metric that favors regions of high local density. The resulting locally adaptive normal distribution (LAND) is
Georgios Arvanitidis   +2 more
openaire   +3 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Bayesian Nonparametric Modelling of the Return Distribution with Stochastic Volatility [PDF]

open access: yes, 2011
This paper presents a method for Bayesian nonparametric analysis of the return distribution in a stochastic volatility model. The distribution of the logarithm of the squared return is flexibly modelled using an infinite mixture of Normal distributions ...
Jim E. Griffin   +3 more
core   +1 more source

Three-Stage Estimation of the Mean and Variance of the Normal Distribution with Application to an Inverse Coefficient of Variation with Computer Simulation

open access: yesMathematics, 2019
This paper considers sequentially two main problems. First, we estimate both the mean and the variance of the normal distribution under a unified one decision framework using Hall’s three-stage procedure. We consider a minimum risk point estimation
Ali Yousef, Hosny Hamdy
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Physical Fitness Indices for Data with Non-normal Distribution

open access: yes, 2012
[[abstract]]At present, there are only few tools on the evaluation of group physical fitness. Hung proposed physical fitness indices based on the process capability indices (PCI) to assess physical fitness level.
許昌賢;Hsu, Chang-Hsien;Chang-Hung Hung
core  

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