Results 81 to 90 of about 15,810,582 (396)

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

A completion simulator for the two-sided truncated normal distribution

open access: yesGenetics Selection Evolution, 2000
This paper presents simulation formulae of two-sided truncated normal random variables using a completion distribution and its two corresponding conditionals generated via a Gibbs sampler.
Foulley Jean-Louis
doaj   +1 more source

Normality for Non-normal Distributions

open access: yesJournal of Science and Mathematics Letters, 2020
It has been usually assumed that a sample data is normally distributed when the sample size is at least 30. This is the general rule in using central limit theorem based on the sample size being greater or equal to 30. Many literary works also assumed normality when sample size is at least 30. This study aims to determine the least required sample size
Nor Aishah Ahad, Khong Liang Koh
openaire   +3 more sources

A log-Birnbaum-Saunders Regression Model with Asymmetric Errors

open access: yes, 2010
The paper by Leiva et al. (2010) introduced a skewed version of the sinh-normal distribution, discussed some of its properties and characterized an extension of the Birnbaum-Saunders distribution associated with this distribution.
Lemonte, Artur J.
core   +1 more source

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

On the Conditional Distribution of a Multivariate Normal given a Transformation - the Linear Case

open access: yes, 2018
We show that the orthogonal projection operator onto the range of the adjoint of a linear operator $T$ can be represented as $UT,$ where $U$ is an invertible linear operator.
Majumdar, Rajeshwari, Majumdar, Suman
core   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Development of Scheduling System Considering Statistical Distributions of Processing Times for Human Operators

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2012
A new scheduling method is proposed, in this paper, to consider the statistical distributions of the processing times which are represented by normal distributions for the manufacturing systems where the human operators carry out the machining operations
Koji IWAMURA   +3 more
doaj   +1 more source

The exp-normal distribution is infinitely divisible [PDF]

open access: yesarXiv, 2018
Let $Z$ be a standard normal random variable (r.v.). It is shown that the distribution of the r.v. $\ln|Z|$ is infinitely divisible; equivalently, the standard normal distribution considered as the distribution on the multiplicative group over $\mathbb{R}\setminus\{0\}$ is infinitely divisible.
arxiv  

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

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