Results 81 to 90 of about 576,763 (311)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

INTERNAL STRUCTURE OF FAULT ZONES: SPATIAL AND TEMPORAL EVOLUTION STUDIES ON CLAY MODELS

Геодинамика и тектонофизика, 2015
Based on results obtained from experiments on clay models, it appeared possible to establish main regularities in the evolution of normal and strike-slip zones which structures are formed heterogeneously in time and space.
Konstantin Zh Seminsky
doaj   +1 more source

Detailed Analysis of Structures in the Foot Wall of the Champlain Thrust at Lone Rock Point, Burlington, Vermont [PDF]

, 2015
The objective of this project was to identify a strain gradient and relative chronology within the foot wall of the Champlain Thrust Fault at Lone Rock Point, Burlington, Vermont in order to determine how the unique fault-bounded ellipsoidal lozenge ...
Strathearn, Christina Marie
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Permeability evolution across carbonate hosted normal fault zones [PDF]

, 2016
Acknowledgements: The authors would like to thank Total E&P and BG Group for project funding and support, and the Industry Technology Facilitator for facilitating the collaborative development (grant number 3322PSD).
Haines, Thomas J., Healy, David, Michie, Emma A. H., Neilson, Joyce E.   +3 more
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

X- and C-Band SAR Surface Displacement for the 2013 Lunigiana Earthquake (Northern Italy): A Breached Relay Ramp?

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2014
In this paper, we applied the differential interferometric synthetic aperture radar (DInSAR) technique to investigate and measure surface displacements due to the Mw 5.3 (M1 5.2), June 21, 2013 earthquake, occurred north of the Apuan Alps (NW Italy), in ...
Salvatore Stramondo, Paola Vannoli, Valentina Cannelli, Marco Polcari, Daniele Melini, Sergey Samsonov, Marco Moro, Christian Bignami, Michele Saroli   +8 more
doaj   +1 more source

Possible role of crustal flexure in the initial detachment of extensional allochthons [PDF]

The existence of low-angle normal faults indicates that the ratio of shear stress (TAU) to normal stress (sigma sub N) needed to cause slip on faults is substantially less than would be predicted based on experimental data. Because the tensional strength
Spencer, J. E.
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Investigation of the Relationship of Earthquakes and Underground Waste Disposal in The El Dorado Area, Arkansas [PDF]

, 1991
From December, 1983 to September, 1989 twelve small earthquakes were recorded for the El Dorado, Arkansas area. Magnitudes of these earthquakes were well below damaging levels.
Cox, Randel, VanArsdale, Roy B.
core   +2 more sources