Results 91 to 100 of about 585,422 (289)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Advances in High Energy Physics, 2019 Inspired by the experimental anomalies in neutrino physics and recent oscillation data from short baseline and another neutrino experiment, the realization of one extra neutrino flavor seems to be favoring.
Jaydip Singh
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Exploring atmospheric neutrino oscillations at ESSnuSB
Journal of High Energy PhysicsThis study provides an analysis of atmospheric neutrino oscillations at the ESSnuSB far detector facility. The prospects of the two cylindrical Water Cherenkov detectors with a total fiducial mass of 540 kt are investigated over 10 years of data taking ...
The ESSnuSB collaboration +87 more
doaj +1 more source
The fate of hints: updated global analysis of three-flavor neutrino oscillations
Journal of High Energy Physics, 2020 Our herein described combined analysis of the latest neutrino oscillation data presented at the Neutrino2020 conference shows that previous hints for the neutrino mass ordering have significantly decreased, and normal ordering (NO) is favored only at the
Ivan Esteban +4 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
An SU(5)×A5 golden ratio flavour model
Nuclear Physics B, 2015 In this paper we study an SU(5)×A5 flavour model which exhibits a neutrino mass sum rule and golden ratio mixing in the neutrino sector which is corrected from the charged lepton Yukawa couplings.
Julia Gehrlein +3 more
doaj +1 more source
The Charge Ordered State from Weak to Strong Coupling
, 1998 We apply the Dynamical Mean Field Theory to the problem of charge ordering. In the normal state as well as in the Charge Ordered (CO) state the existence of polarons, i.e.
A. Bianconi +29 more
core +2 more sources
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source