Results 251 to 260 of about 3,820,734 (347)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Evaluation of diversity and effective traits in Iranian cotton germplasm. [PDF]

PLoS One
Najjar H, Mahdi Nezhad N, Taherian M, Fakheri BA, Allahdou M, Ramazani Moghadam MR.   +5 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Saturation behavior and full-field reconstruction of residual stress in quenched AISI 304 stainless steel via the contour method. [PDF]

Sci Rep
Meng L, Khan AM, Shan Y, Al-Ghamdi KA.
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Interactive effects of calcium-nitrogen combined stress and nitrogen forms on nitrogen metabolism and physiological ecological response mechanisms of <i>Toona sinensis</i> Seedlings. [PDF]

Front Plant Sci
Hang H, Guo G, Li C, Zhang Y.
europepmc   +1 more source

Measurement of Normal Stress Differences of High Density and Low Density Polyethylene Melts by Use of an Experimental Improved Weissenberg-Rheogoniometer

, 1979
Kensei Hayashida, Yoshimasa Okuda
openalex   +2 more sources

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Epigenetic regulation of the glucocorticoid receptor gene through methylation is linked to post-traumatic stress disorder. [PDF]

Sci Rep
Ye M, Lee HJ, Shim I.
europepmc   +1 more source

Fasting-based differential stress resistance to enhance cancer treatment: a novel strategy to protect normal cells and sensitize cancer cells to chemotherapy

, 2015
Changhan Lee
openalex   +1 more source