Results 121 to 130 of about 1,041,285 (289)

Normalized solutions of Schrödinger equations involving Moser-Trudinger critical growth

open access: yesAdvances in Nonlinear Analysis
In this article, we are concerned with the nonlinear Schrödinger equation −Δu+λu=μ∣u∣p−2u+f(u),inR2,-\Delta u+\lambda u=\mu {| u| }^{p-2}u+f\left(u),\hspace{1em}\hspace{0.1em}\text{in}\hspace{0.1em}\hspace{0.33em}{{\mathbb{R}}}^{2}, having prescribed ...
Li Gui-Dong, Zhang Jianjun
doaj   +1 more source

Normalized solutions for planar Schrödinger–Poisson equation with mixed nonlinearities

open access: yesBulletin of Mathematical Sciences
This paper deals with the following Schrödinger–Poisson equation with mixed nonlinearities: −Δu+λu+12π(ln|⋅|∗|u|2)u=μ|u|q−2u+|u|p−2u,x∈ℝ2,∫ℝ2u2dx=c, where [Formula: see text], [Formula: see text], [Formula: see text], [Formula: see text] is a given real ...
Muhua Shu, Lixi Wen, Heng Yang
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Existence of normalized solutions for Schrödinger systems with linear and nonlinear couplings

open access: yesBoundary Value Problems
In this paper we study the nonlinear Bose–Einstein condensates Schrödinger system { − Δ u 1 − λ 1 u 1 = μ 1 u 1 3 + β u 1 u 2 2 + κ ( x ) u 2 in  R 3 , − Δ u 2 − λ 2 u 2 = μ 2 u 2 3 + β u 1 2 u 2 + κ ( x ) u 1 in  R 3 , ∫ R 3 u 1 2 = a 1 2 , ∫ R 3 u 2 2 =
Zhaoyang Yun, Zhitao Zhang
doaj   +1 more source

Multiple normalized solutions for $(2,q)$-Laplacian equation problems in whole $\mathbb{R}^{N}$

open access: yesElectronic Journal of Qualitative Theory of Differential Equations
This paper considers the existence of multiple normalized solutions of the following $(2,q)$-Laplacian equation: \begin{equation*} \begin{cases} -\Delta u-\Delta_q u=\lambda u+h(\epsilon x)f(u), &\mathrm{in}\ \mathbb{R}^{N},\\ \int_{\mathbb{R}^{N}}|u|^
Renhua Chen, Li Wang, Xin Song
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Existence of solutions to a normalized F-infinity Laplacian equation

open access: yesElectronic Journal of Differential Equations, 2014
In this article, for a continuous function F that is twice differentiable at a point $x_0$, we define the normalized F-infinity Laplacian $\Delta_{F; \infty}^N$ which is a generalization of the usual normalized infinity Laplacian. Then for a bounded
Hua Wang, Yijun He
doaj  

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