Results 131 to 140 of about 7,704,118 (361)

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

open access: yesMolecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song   +13 more
wiley   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Normalized solutions to a class of (2, q)-Laplacian equations

open access: yesAdvanced Nonlinear Studies
This paper is concerned with the existence of normalized solutions to a class of (2, q)-Laplacian equations in all the possible cases with respect to the mass critical exponents 2(1 + 2/N), q(1 + 2/N).
Baldelli Laura, Yang Tao
doaj   +1 more source

Solution of rank deficient normals

open access: yes, 1981
Technical note written as input to the early studies of the ESA space astrometry project Hipparcos.
openaire   +2 more sources

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Existence of normalized solutions for a Sobolev supercritical Schrödinger equation

open access: yesElectronic Research Archive
This paper studies the existence of normalized solutions for the following Schrödinger equation with Sobolev supercritical growth: \begin{document}$ \begin{equation*} \begin{cases} -\Delta u+V(x)u+\lambda u = f(u)+\mu |u|^{p-2}u, \quad &\hbox{in ...
Quanqing Li, Zhipeng Yang
doaj   +1 more source

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