Results 131 to 140 of about 294,135 (314)
A METHOD FOR THE SOLUTION OF NORMAL EQUATIONS
A new method of solving normal equations is presented. A comparison is made of the application of the method to a multiple regression case used by Dwyer to illustrate his abbreviation of the Doolittle method. The proposed method for relatively, small numbers of unknowns at least, is simpler than Dwyer's method, considered to date to be one, if not the ...
openaire +2 more sources
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Normalized solutions for Sobolev critical Schrodinger-Bopp-Podolsky systems
Yuxin Li, Xiaojun Chang, Zhaosheng Feng
doaj
Normalized solutions of Schrödinger equations involving Moser-Trudinger critical growth
In this article, we are concerned with the nonlinear Schrödinger equation −Δu+λu=μ∣u∣p−2u+f(u),inR2,-\Delta u+\lambda u=\mu {| u| }^{p-2}u+f\left(u),\hspace{1em}\hspace{0.1em}\text{in}\hspace{0.1em}\hspace{0.33em}{{\mathbb{R}}}^{2}, having prescribed ...
Li Gui-Dong, Zhang Jianjun
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
SOLUTIONS OF GASES IN NORMAL LIQUIDS [PDF]
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The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Normalized solutions for Schödinger equations with potential and general nonlinearities involving critical case on large convex domains [PDF]
Jun Wang, Zhaoyang Yin
openalex +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source

