Results 141 to 150 of about 8,131,330 (355)

Levothyroxine Sodium Oral Solution Normalizes Thyroid Function in a Patient with Hashimoto’s Disease, Gastritis, Diabetic Gastroparesis, and Small Intestinal Bacterial Overgrowth (SIBO)

, 2021
Brittany Bohinc Henderson
openalex   +2 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Multiple normalized solutions for $(2,q)$-Laplacian equation problems in whole $\mathbb{R}^{N}$

Electronic Journal of Qualitative Theory of Differential Equations
This paper considers the existence of multiple normalized solutions of the following $(2,q)$-Laplacian equation: \begin{equation*} \begin{cases} -\Delta u-\Delta_q u=\lambda u+h(\epsilon x)f(u), &\mathrm{in}\ \mathbb{R}^{N},\\ \int_{\mathbb{R}^{N}}|u|^
Renhua Chen, Li Wang, Xin Song
doaj   +1 more source

A normalized algorithm for the solution of sparse symmetric seven-diagonal linear systems of semi-bandwidths M and P

, 1981
Elias A. Lipitakis
openalex   +1 more source

Multiple positive normalized solutions for nonlinear Schrödinger systems [PDF]

, 2018
Tianxiang Gou, Louis Jeanjean
openalex   +1 more source

Multiple normalized solutions for a Sobolev critical Schrödinger-Poisson-Slater equation

, 2021
Louis Jeanjean, Thanh Trung Le
openalex   +2 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Multiple Normalized Solutions for Choquard equations involving Kirchhoff type perturbation [PDF]

, 2019
Zeng Liu
openalex   +1 more source

Normalized solutions for Schrödinger equations with critical Sobolev exponent and mixed nonlinearities

, 2021
Juncheng Wei, Yuanze Wu
openalex   +2 more sources

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source