Results 141 to 150 of about 994,574 (330)
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva+5 more
wiley +1 more source
Blow-up solutions to the Hartree-Fock type Schrödinger equation with the critical rotational speed
In this article, we are concerned with the existence, non-existence, and blow-up behavior of normalized ground state solutions for the mass critical Hartree-Fock type Schrödinger equation with rotation i∂tu=−Δu+2V(x)u+2ΩLzu−λu−bu∫RN∣u(y)∣2∣x−y∣2dy,(t,x ...
Tu Yuanyuan, Wang Jun
doaj +1 more source
Normalized solutions to the fractional Kirchhoff equations with combined nonlinearities
Lintao Liu, Haibo Chen, Jie Yang
openalex +2 more sources
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo+11 more
wiley +1 more source
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková+14 more
wiley +1 more source
Normalized solutions for nonlinear Schrödinger systems with critical exponents
In this paper, we consider the following nonlocal Schrödinger system−a+b∫R3|∇u1|2dxΔu1=λ1u1+μ1|u1|p1−2u1+βr1|u1|r1−2u1|u2|r2,−a+b∫R3|∇u2|2dxΔu2=λ2u2+μ2|u2|p2−2u2+βr2|u1|r1|u2|r2−2u2,∫R3|u1|2dx=c1,∫R3|u2|2dx=c2.
Hu Jiaqing, Mao Anmin
doaj +1 more source
Existence of normalized solutions for a Sobolev supercritical Schrödinger equation
This paper studies the existence of normalized solutions for the following Schrödinger equation with Sobolev supercritical growth: \begin{document}$ \begin{equation*} \begin{cases} -\Delta u+V(x)u+\lambda u = f(u)+\mu |u|^{p-2}u, \quad &\hbox{in ...
Quanqing Li, Zhipeng Yang
doaj +1 more source