Results 151 to 160 of about 299,484 (312)

Normalized Solutions to the Mixed Fractional Schrödinger Equations With Potential and General Nonlinear Term [PDF]

Anouar Bahrouni, Qi Guo, Hichem Hajaiej
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Existence of normalized solutions for the mixed fractional Laplacians equation with different types of potentials [PDF]

Xu Fang, Xin Qiu, Zeng‐Qi Ou, Ying Lv
openalex   +1 more source

SOLUTIONS OF GASES IN NORMAL LIQUIDS [PDF]

Proceedings of the National Academy of Sciences, 1967
openaire   +2 more sources

Normalized ground state solutions for Kirchhoff equation with subcritical or critical perturbation

Electronic Journal of Differential Equations
This article concerns the Kirchhoff equation with subcritical or critical perturbation. We establish the existence of normalized ground state solutions by using Pohozaev manifold and subcritical approximation methods.
Zian Fan
doaj  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Changes in Water Dynamics by Osmolytes Regulate Enzyme Activity. [PDF]

J Phys Chem B
Furukawa S, Hishida M.
europepmc   +1 more source

Existence of normalized solutions for Schrödinger systems with linear and nonlinear couplings [PDF]

Zhaoyang Yun, Zhitao Zhang
openalex   +1 more source

Pix2Pix-based Stain-to-Stain Translation: A Solution for Robust Stain Normalization in Histopathology Images Analysis [PDF]

, 2020
Pegah Salehi, Abdolah Chalechale
openalex   +1 more source