Results 81 to 90 of about 294,135 (314)

Multiplicity and orbital stability of normalized solutions to non-autonomous Schrödinger equation with mixed nonlinearities [PDF]

, 2022
Xinfu Li, Xu Li, Meiling Zhu
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Normalized solutions for the Kirchhoff equation with combined nonlinearities in ℝ4

Advances in Nonlinear Analysis
In this article, we study the following Kirchhoff equation with combined nonlinearities: −a+b∫R4∣∇u∣2dxΔu+λu=μ∣u∣q−2u+∣u∣2u,inR4,∫R4∣u∣2dx=c2,\left\{\begin{array}{l}-\left(a+b\mathop{\displaystyle \int }\limits_{{{\mathbb{R}}}^{4}}{| \nabla u| }^{2}{\rm ...
Qiu Xin, Ou Zeng-Qi, Tang Chun-Lei, Lv Ying   +3 more
doaj   +1 more source

Normalized solutions for Kirchhoff equations with Choquard nonlinearity: mass Super-Critical Case

Communications in Analysis and Mechanics
In the present paper, we investigated the existence of normalized solutions for the following Kirchhoff equation with Choquard nonlinearity$ \begin{equation*} -\Big(a+b\int_{\mathbb{R}^{3}}|\nabla u|^{2}dx\Big)\Delta u-\lambda u = \mu|u|^{q-2}u+(I_ ...
Zhi-Jie Wang, Hong-Rui Sun
doaj   +1 more source

Equivalence of viscosity and weak solutions for the normalized p(x)-Laplacian [PDF]

, 2018
Jarkko Siltakoski
openalex   +1 more source

Normal solutions of linear programs [PDF]

, 1984
The author introduces the definition of normal solution to a linear program, which is an exact solution with some least norm property if the linear program is solvable, otherwise an approximate solution with some least norm property also. By considering normal solutions we are led to (i) iterative successive overrelaxation (SOR) methods capable of ...
openaire   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Normalized solutions for Sobolev critical fractional Schrödinger equation

Advances in Nonlinear Analysis
In the present study, we investigate the existence of the normalized solutions to Sobolev critical fractional Schrödinger equation: (−Δ)su+λu=f(u)+∣u∣2s*−2u,inRN,(Pm)∫RN∣u∣2dx=m2,\hspace{14em}\left\{\begin{array}{ll}{\left(-\Delta )}^{s}u+\lambda u=f ...
Li Quanqing, Nie Jianjun, Wang Wenbo, Zhou Jianwen   +3 more
doaj   +1 more source