Results 61 to 70 of about 490,657 (289)

Bulk magnetization and strong intrinsic pinning in Ni-doped BaFe2As2 single crystals

open access: yes, 2012
We report on measurements of isothermal irreversible magnetization loops (M(H)) of Ni-doped BaFe2-xNixAs2 single crystals with x=0.1 and x=0.14 in magnetic fields up to 14T.
Eltsev, Yu. F.   +5 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Pancreatico-pleural fistula mimicking a recurrent congenital diaphragmatic hernia: A case report

open access: yesJournal of Pediatric Surgery Case Reports
Introduction: Pancreaticopleural fistula (PPF) is a very rare complication of pancreatitis. The symptoms are non-specific and the diagnosis is often missed.
Maximilian Holweg   +5 more
doaj   +1 more source

Boundary driven zero-range processes in random media

open access: yes, 2007
The stationary states of boundary driven zero-range processes in random media with quenched disorder are examined, and the motion of a tagged particle is analyzed.
A.V. Skorohod   +39 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Time-resolved electron beam phase space tomography at a soft x-ray free-electron laser

open access: yesPhysical Review Special Topics. Accelerators and Beams, 2009
High-gain free-electron lasers (FELs) in the ultraviolet and x-ray regime put stringent demands on the peak current, transverse emittance, and energy spread of the driving electron beam.
Michael Röhrs   +4 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Dynamic margin contrastive learning for open-set recognition in long-tailed sonar imagery

open access: yesScientific Reports
Long-tail distribution and open-set recognition remain significant challenges in sonar image classification. This study introduces Dynamic Margin Contrastive Learning (DMCL), a novel framework that simultaneously addresses both issues through adaptive ...
Yu Lin, Shuiyuan He, Weidong Luo
doaj   +1 more source

Treatment of CoQ(10) deficient fibroblasts with ubiquinone, CoQ analogs, and vitamin C: time- and compound-dependent effects.

open access: yesPLoS ONE, 2010
BackgroundCoenzyme Q(10) (CoQ(10)) and its analogs are used therapeutically by virtue of their functions as electron carriers, antioxidant compounds, or both.
Luis C López   +8 more
doaj   +1 more source

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