Results 91 to 100 of about 5,411,218 (297)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Distribution of Iron Sheet Sand in Chengdao Area

Haiyang Kaifa yu guanli
Iron plate sand is a special sedimentary geomorphology existing in the underwater delta of the Yellow River. It is formed by the widespread development of silt beds on the seabed, resulting in a distinct hard layer of sedimentand is commonly called "iron
JIANG Yue, WANG Penglei, LYU Zhiwei, ZHANG Wang   +3 more
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Confluence : Spring/Summer 2018 - accessible version

Confluence is a newsletter of Oregon Sea Grant.
Oregon State University. Sea Grant College Program
core   +2 more sources

Confluence : Fall/Winter 2017 [PDF]

Confluence is a newsletter of Oregon Sea Grant. Articles feature the supported research and events of the program. This issue of Confluence includes articles on: potential of farming gooseneck barnacles, educating boaters on proper waste disposal ...
Oregon State University. Sea Grant College Program
core   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Effects of Dietary Vitamin A on the Growth Performance, Nonspecific Immune Response, Shell Microbiota and Red Spotted Disease Resistance of Juvenile Sea Urchin (Strongylocentrotus intermedius)

Aquaculture Nutrition
A 114-day feeding trial was used to investigate the influence of vitamin A (VA) on growth performance, nonspecific immune responses and shell microbiota in juvenile sea urchin (Strongylocentrotus intermedius).
Dan Gou, Rujian Xu, Haijing Liu, Panke Gong, Weixiao Di, Huinan Zuo, Jun Ding, Yaqing Chang, Rantao Zuo   +8 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Machine learning-based assessment of offshore wind farm impacts on soft-bottom benthic communities in the Shandong Peninsula

Scientific Reports
Offshore wind power, as a crucial component of clean energy, is rapidly expanding globally; however, the long-term impact mechanisms on marine benthic ecosystems remain unclear.
Lan Wang, Yongqiang Zhang, Xueji Gu, Liang Zhang, Haizhou Zhang, Kai Su, Chuanting Zhao   +6 more
doaj   +1 more source

Seasonal Variation in Zooplankton Community Structure and Its Environmental Drivers in the Coastal Waters of Lanshan Port

Biology
Coastal port ecosystems serve as critical interfaces between marine environments and anthropogenic activities, yet zooplankton community dynamics in these transitional zones remain poorly understood.
Liang Zhang, Lan Wang, Cong Fang, Yinglu Ji, Sichao Pu, Huihui Tao, Haizhou Zhang, Yumeng Liu   +7 more
doaj   +1 more source