Results 211 to 220 of about 178,608 (339)

Northern Blot [PDF]

, 2019
openaire   +1 more source

Tau‐targeting active immunotherapy slows progression and reduces pathology in mouse models of tauopathy

Brain Pathology, EarlyView.
The efficacy of the novel anti‐tau active immunotherapy, p5555kb, was tested using two mouse models of tau pathology. p5555kb inoculation increased the survival rate and reduced tau pathology in tau‐overexpressing P301L mice and decreased tau seeding in the brains of C57BL/6 mice injected with human‐purified Alzheimer's disease tau.
Christopher M. Brown, Jeanne K. Brooks, Louise Kelly, Madeline M. Vroom, Matthew Longo, Jean‐Cosme Dodart, Roxana Carare, Justin D. Boyd   +7 more
wiley   +1 more source

Enhanced microRNA accumulation and gene silencing efficiency through optimized precursor base pairing. [PDF]

Plant J
Llorens-Gámez JJ, García-Cano PJ, Rico-Rodrigo S, Duyos-Casanova L, Toledano-Franco S, Carbonell A.   +5 more
europepmc   +1 more source

Role of the stage-regulated nucleoside transporter TbNT10 in differentiation and adenosine uptake in Trypanosoma brucei [PDF]

, 2007
Al-Salabi, Burchmore, Burkard, Carter, Christina Kunz Renggli, de Koning, de Koning, de Koning, Delauw, Domenicali Pfister, Flück, Gabriela Burkard, Geiser, Hammond, Iris Spoerri, Isabel Roditi, Keith Matthews, Le Ray, Liniger, Mäser, Ruth Chadwick, Sanchez, Sanchez, Vassella, Vassella, Vickerman   +25 more
core   +2 more sources

Enhanced Annexin I mRNA in human hepatoma and cirrhosis.Examination using Northern blot,in situ hybridization.

, 1994
TSUTOMU MASAKI
openalex   +2 more sources

Opioids in breast cancer: Between analgesia and modulation of tumour progression

British Journal of Pharmacology, EarlyView.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun, Anna Tankiewicz‐Kwedlo, Dariusz Pawlak   +2 more
wiley   +1 more source

DICER1 hotspot mutation induces 3p microRNA gain of function via Argonaute strand switch. [PDF]

Nat Struct Mol Biol
Malagobadan S, Shi C, Yang A, Mondal I, Baldeh H, Spain K, Guiblet W, Gu S.   +7 more
europepmc   +1 more source

Dysregulation of Rho‐Associated Coiled‐Coil Protein Kinase1 Depletes Neural Stem Cell Pool and Impairs Hippocampal Neurogenesis After Traumatic Brain Injury

Cell Proliferation, EarlyView.
Following TBI, hippocampal neurogenesis in mice is impaired and affects cognitive function. This impairment is associated with the upregulation of p‐AKT/AKT mediated by ROCK1. ABSTRACT Traumatic brain injury (TBI) represents a global health burden, often resulting in persistent neurological deficits due to impaired hippocampal neurogenesis ...
Chaoqun Yao, Long Jin, Jun Zhong, Qianying Huang, Zhongwei Bao, Shaolong Zhou, Chaohua Wang, Huanhuan Li, Xiaowei Yuan, Zhen Wang, Ning Du, Jingxuan Yu, Huanran Chen, Xuyang Zhang, Hongfei Ge, Jianheng Wu   +15 more
wiley   +1 more source

Interferon alpha-inducible protein 27 (IFI27) inhibits hepatitis B virus (HBV) transcription through downregulating cellular transcription factor C/EBPα. [PDF]

J Virol
Yu X, Liu C-D, Shen S, Kim ES, Liu Z, Zhang H, Sun N, Liu Y, Martensen PM, Huang Y, Guo H.   +10 more
europepmc   +1 more source

Climate shocks, democratization and (a culture of) cooperation

Economica, EarlyView.
Abstract While the direct economic effects of adverse climate shocks are well known, their indirect institutional impact is still poorly understood. To clarify this, we test the idea that adverse climate shocks push time‐inconsistent elites to enact inclusive political institutions, and non‐elites to embrace strong norms of cooperation.
Giacomo Benati, Carmine Guerriero
wiley   +1 more source