Results 131 to 140 of about 296,712 (303)
Defined PEG hydrogels enable human iPSC‐derived intestinal organoid culture without Matrigel. PEG‐ and Matrigel‐cultured organoids both support duodenal‐like epithelial identity, but direct comparison reveals subtle epithelial differentiation‐marker shifts and stronger mesenchymal ECM‐remodeling/integrin programs in PEG.
Alicja Kuziola +8 more
wiley +1 more source
Soft dielectric elastomer composites often face a trade‐off between enhanced dielectric properties and mechanical compliance. Here, a parallel‐aligned polyurethane nanofiber network embedded in PDMS creates a flexible, durable composite with increased permittivity, low modulus, and fatigue stability after 100,000 cycles.
Yi Ge +9 more
wiley +1 more source
Nanoimprint lithography can replicate complex 3D microstructures with undercuts using single‐layer polymer stamps of different elasticities. By combining experiments and simulations, T‐shaped geometries and suitable undercut radii were identified that minimize stress and defects during demolding.
Christos Julianos Karapatzakis +3 more
wiley +1 more source
Implantation of the blastocyst involves numerous hormonal and cellular factors with Notch playing a key role, according to a new study suggesting that this developmental regulator may help modulate expression of the progesterone receptor. In previous studies, Asgi Fazleabas and colleagues have shown that conditionally deleting Notch1 in the mouse ...
openaire +2 more sources
Micromachined Double‐Membrane Mechanically Tunable Metamaterial for Thermal Infrared Filtering
Herein, a mechanically tunable double‐layer plasmonic metamaterial leveraging the extraordinary optical transmission effect observed in subwavelength arrays of openings within thin metal layers is presented. The concept is experimentally validated by integrating the proposed metamaterial structure into an electrostatic parallel‐plate actuator to create
Oleg Bannik +7 more
wiley +1 more source
Continuum Mechanics Modeling of Flexible Spring Joints in Surgical Robots
A new mechanical model of a tendon‐actuated helical extension spring joint in surgical robots is built using Cosserat rod theory. The model can implicitly handle the unknown contacts between adjacent coils and numerically predict spring shapes from straight to significantly bent under actuation forces.
Botian Sun +3 more
wiley +1 more source
Hybrid Continuum Robot Designs and Architectures for Healthcare Applications
Hybrid continuum robots represent an emerging class of flexible manipulators that blend materials, structures, and actuation concepts from the established fields of soft and continuum robotics. This review introduces an accessible framework to distinguish key hybridization approaches, surveys current designs aimed at complex clinical applications, and ...
Burak Ozdemir +4 more
wiley +1 more source
Flexible surgical robots are advancing minimally invasive interventions for cardiovascular diseases and cancer by enabling precise navigation through complex, submillimeter anatomical pathways. This review highlights recent innovations in actuation, bio‐integrated sensing, AI‐assisted control, and friction‐reduction technologies, discusses current ...
Hermione Truong +14 more
wiley +1 more source
Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang +9 more
wiley +1 more source

