Results 181 to 190 of about 118,516 (288)

Prognostic and predictive impact of NOTCH1 mutations in patients with chronic lymphocytic leukemia: a tertiary single-center experience. [PDF]

Front Oncol
D'Antiga M, Serafin A, Angotzi F, Cellini A, Bevilacqua A, Leone G, Danesin N, Cavarretta CA, Piazza F, Piovan E, Bonaldi L, Trentin L, Visentin A.   +12 more
europepmc   +1 more source

A review of xenobiotic membrane transporter expression within the human placenta: Lessons gained from primary tissue and in vitro methodologies

The Journal of Physiology, EarlyView.
Abstract figure legend A summary of the current knowledge around membrane transporter expression in the most widely used in vitro models of human trophoblasts, including primary placental tissue, cancer cell lines and trophoblast stem cells, as well as the techniques to attempt to mimic the human placenta in vivo.
Rhiannon Pass, Kathryn Wolton, Amanda N. Sferruzzi‐Perri   +2 more
wiley   +1 more source

DNA methylation analysis of NOTCH1 variants reveals the first episignature for non-syndromic congenital heart defects. [PDF]

Genome Med
Dombrowsky G, van der Laan L, Silva A, Breckpot J, Audain E, Wilsdon A, Levy MA, Vos N, Mannens M, Wang J, Jain A, Lesurf R, Winlaw D, Bezzina CR, Thomas MA, Caliebe A, Klaassen S, Berger F, Dittrich S, Stiller B, Abdul-Khaliq H, Dähnert I, Bu'Lock F, Loughna S, Brook JD, Mital S, Russell RB, Pickardt T, Bauer U, Kramer HH, Uebing A, Henneman P, Sadikovic B, Postma A, Hitz MP.   +34 more
europepmc   +1 more source

Signaling by NOTCH1

Reactome - a curated knowledgebase of biological pathways, 2012
openaire   +1 more source

Notch 1 (NOTCH1) [PDF]

Science-Business eXchange, 2012
openaire   +1 more source

Mechanistic role of GNE‐987 targeting BRD4‐HCP5 axis in pediatric T‐cell acute lymphoblastic leukemia

Journal of Cell Communication and Signaling, Volume 20, Issue 1, March 2026.
Abstract This study aims to explore the mechanism of action of the Bromodomain‐containing protein 4 (BRD4) inhibitor GNE‐987 in the treatment of pediatric T‐cell Acute Lymphoblastic Leukemia (T‐ALL), focusing on its effect in inhibiting T‐ALL cell proliferation by activating the HLA Complex P5 (HCP5) Super‐enhancer.
Xu Sang, Mengying Jiang, Yanchun Guan, Xin Chen, Zhen Zhang, Yumeng Wu, Wansheng Peng   +6 more
wiley   +1 more source

Notch1⁺ cervical cancer cells may promote perineural invasion by secreting neurotrophin-4. [PDF]

Sci Rep
Li F, Wei Z, Tao M, Zhao K, Wang L, Chen X, Wang Y.   +6 more
europepmc   +1 more source

Biopsy for Suspicious Oral Lesions: A Review From the American Head and Neck Society‐Cancer Prevention Service

Head &Neck, Volume 48, Issue 3, Page 884-892, March 2026.
ABSTRACT Background Oral cancer is often preceded by a precursor lesion. This presents an opportunity for early diagnosis and intervention. Method of biopsy and interpretation are not well standardized and novel methods of analysis are now being investigated.
James Christopher Gates, Heather Edwards, Alessandro Villa, Nick Purdy, Michael Troka, Peter Varela, Quinn Self, Yingci Liu, Yusuf Dundar, Patricia Joyce Brooks, Dauren Adilbay, Andrew Birkeland, John Cramer   +12 more
wiley   +1 more source

Non-canonical NOTCH1 signaling regulates ferroptosis vulnerability in dormant lung cancer cells with stable resistance. [PDF]

Cell Death Dis
Huang H, Chai Y, Wu X, Wang S, Li B, Wang Y, Zheng W, Wu Y, Meng D, Wang H, Tu Z, Du C, Lyu X, Li G, Guo W.   +14 more
europepmc   +1 more source

Tumor‐infiltrating B cells participate in shaping the immunosuppressive microenvironment in solid tumors

International Journal of Cancer, Volume 158, Issue 5, Page 1156-1165, 1 March 2026.
Abstract Tumor‐infiltrating B cells (TIBs) exhibit dual roles in the tumor microenvironment (TME) of solid tumors. While they can enhance anti‐tumor immunity through antibody production and immune activation, certain subsets—such as regulatory B cells (Bregs) and immunosuppressive plasma cells—contribute to immune evasion by secreting inhibitory ...
Zhitong Li, Ziyang Shen, Yuxiang Sun, Pengcheng Zhu, Tongyan Liu, Rong Yin   +5 more
wiley   +1 more source