Results 241 to 250 of about 119,232 (259)

NOTCH1 Mutation

2016
openaire   +1 more source

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

Nature Medicine, 2007
Teresa Palomero, Maria Ciofani, Esther Caparrós   +2 more
exaly  

Complementary Genomic Screens Identify SERCA as a Therapeutic Target in NOTCH1 Mutated Cancer

Cancer Cell, 2013
Giovanni Roti, Anne L Carlton, Michele Markstein   +2 more
exaly  

Structural basis for Notch1 engagement of Delta-like 4

Science, 2015
Vincent C Luca, Kevin M Jude, Maxence V Nachury   +2 more
exaly  

Notch1 Signaling in Neuroblastoma

Journal of Surgical Research, 2012
J.F. Burke, Q. Khan, S. Kunnimalaiyaan, M. Roy, M. Kunnimalaiyaan   +4 more
openaire   +1 more source

Human Disease Modeling Reveals Integrated Transcriptional and Epigenetic Mechanisms of NOTCH1 Haploinsufficiency

Cell, 2015
Christina V Theodoris, Katherine S Pollard, Benoit G Bruneau   +2 more
exaly  

A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia

Nature Medicine, 2014
Daniel Herranz, Alberto Ambesi-Impiombato, Teresa Palomero   +2 more
exaly  

Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia

Nature Medicine, 2015
Daniel Herranz, Alberto Ambesi-Impiombato, Laura Belver   +2 more
exaly  

Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia

Nature, 2014
Monique Dail, Qing Li, Jon C Aster
exaly  

Targeting the NF-κB signaling pathway in Notch1-induced T-cell leukemia

Nature Medicine, 2006
Silvia Buonamici, Maria-Luisa Alegre, Lucio Miele   +2 more
exaly