Results 11 to 20 of about 9,549,485 (300)
Influence Rule of Annular Notch Geometric Parameter on the Tubing Surface: A Case Study
Metals, 2022 In regards to the problem of tubing precision separation, the high-efficiency precision separation method for tubing under eccentric wheel high-speed rotational bending fatigue loading is proposed, which aims to promote the initiation of fatigue cracks ...
Renfeng Zhao +6 more
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The effects of notch size and material microstructure on the notch sensitivity factor for notched components [PDF]
Engineering Fracture Mechanics, 2015 Abstract Nickel base superalloys are used in hot sections of gas turbine engines due to its high strength and good creep, fatigue, and corrosion resistance at high temperature. In this paper, a new probabilistic approach based on weakest-link theory that accounts for the effects of the microstructure, notch size and notch acuity is described and ...
Gbadebo Owolabi +4 more
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Effects of Notch glycosylation on health and diseases [PDF]
Development, Growth & Differentiation, 2019 AbstractNotch signaling is an evolutionarily conserved signaling pathway and is essential for cell‐fate specification in metazoans. Dysregulation of Notch signaling results in various human diseases, including cardiovascular defects and cancer.
Yusuke Urata, Hideyuki Takeuchi
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Metals, 2019 This paper analyzes, using the theory of critical distances, the environmentally assisted cracking behavior of two steels (S420 and API X80) subjected to two different aggressive environments.
Pablo González +3 more
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Notch stimulates growth by direct regulation of genes involved in the control of glycolysis and the tricarboxylic acid cycle [PDF]
Open Biology, 2016 Glycolytic shift is a characteristic feature of rapidly proliferating cells, such as cells during development and during immune response or cancer cells, as well as of stem cells.
Vera Slaninova +6 more
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Stem Cell Research, 2021 Adipose tissue-derived stem cells (ADSCs) have been suggested as a novel treatment for non-alcoholic steatohepatitis (NASH); however, the mechanisms underlying their therapeutic effect remain poorly understood.
Kosuke Ishida +15 more
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Notch Effect on the Fatigue Behavior of a TC21 Titanium Alloy in Very High Cycle Regime
Applied Sciences, 2018 The very high cycle fatigue (VHCF) property of TC21 titanium alloy blunt-notched specimens were investigated by using an ultrasonic fatigue test machine with a frequency of 20 kHz.
Baohua Nie +5 more
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Metals, 2021 The stress state has an important effect on the deformation and failure of metals. While the stress states of the axisymmetric notched bars specimens are studied in the literature, the studies on the flat metal specimen with inclined notch are very ...
Jian Peng +5 more
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The Role of Notch in the Cardiovascular System: Potential Adverse Effects of Investigational Notch Inhibitors [PDF]
Frontiers in Oncology, 2015 Targeting the Notch pathway is a new promising therapeutic approach for cancer patients. Inhibition of Notch is effective in the oncology setting because it causes a reduction of highly proliferative tumor cells and it inhibits survival of cancer stem cells, which are considered responsible for tumor recurrence and metastasis. Additionally, since Delta-
Paola eRizzo +10 more
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Notch activates Wnt-4 signalling to control medio-lateral patterning of the pronephros [PDF]
, 2009 Previous studies have highlighted a role for the Notch signalling pathway during pronephrogenesis in the amphibian Xenopus laevis, and in nephron development in the mammalian metanephros, yet a mechanism for this function remains elusive.
Naylor, Richard +7 more
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