Numb is not a critical regulator of Notch-mediated cell fate decisions in the developing chick inner ear. [PDF]
, 2015 The Notch signaling pathway controls differentiation of hair cells and supporting cells in the vertebrate inner ear. Here, we have investigated whether Numb, a known regulator of Notch activity in Drosophila, is involved in this process in the embryonic ...
Mark eEddison +9 more
core +1 more source
The role of the notch signalling pathway in vascular smooth muscle cell apoptosis [PDF]
, 2004 The Notch signalling system is a highly conserved method of cell-to-cell communication involved in cell fate decisions in many cell types. Until recently, the importance of the Notch signalling pathway was recognized in the embryonic but not in the adult
Sweeney, Catherine Helena
core +2 more sources
Blood flow suppresses vascular Notch signalling via dll4 and is required for angiogenesis in response to hypoxic signalling [PDF]
, 2013 The contribution of blood flow to angiogenesis is incompletely understood. We examined the effect of blood flow on Notch signalling in the vasculature of zebrafish embryos, and whether blood flow regulates angiogenesis in zebrafish with constitutively up-
McMahon, Kathryn +25 more
core +1 more source
Notch signaling pathway in human vascular smooth muscle cell differentiation [PDF]
, 2006 Notch receptor-ligand interactions are a highly conserved mechanism, originally described in developmental studies using Drosophilae, that regulate inter-cell communication and dictate, in part, vascular smooth muscle cell (VSMC) fate in response to ...
Scheller, Agnieszka
core +2 more sources
Analysis of dissipated energy and temperature fields at severe notches of AISI 304L stainless steel specimens [PDF]
Fracture and Structural Integrity, 2019 In the last years, a large amount of fatigue test results from plain and bluntly notched specimens made of AISI 304L stainless steel were synthetized in a single scatter band by adopting the specific heat loss per cycle (Q) as a damage parameter.
D. Rigon, M. Ricotta, G. Meneghetti
doaj +1 more source
The Effect of Notch Filter on RFI Suppression
Wireless Sensor Network, 2009 Radio Frequency Interference (RFI) suppression is an important technique in the ultra-wideband synthetic aperture radar (UWB SAR). In this paper, we mainly analyze the performance of a notch filter for RFI sup-pression. The theoretical output from notch filter is presented based on RFI signal’s narrowband property.
Wenge Chang, Jianyang Li, Xiangyang Li
openaire +3 more sources
Stem Cell Research & Therapy, 2020 Background Prostate cancer stem-like cells (PCSCs) likely participate in tumor progression and recurrence and demonstrate resistance to chemotherapy. The Notch pathway plays a role in the maintenance of the stemness in PCSCs.
Lei Wang +7 more
doaj +1 more source
Fringe controls naïve CD4(+)T cells differentiation through modulating notch signaling in asthmatic rat models. [PDF]
PLoS ONE, 2012 The ability of Notch signaling to regulate T helper cell development and differentiation has been widely accepted. Fringe, O-fucose-β1,3-N-acetylglucosaminyltransferases modulate Notch receptor expression and promote the Notch signaling pathway through ...
Wen Gu, Weiguo Xu, Tao Ding, Xuejun Guo
doaj +1 more source
The molecular role of non-canonical Notch signaling via Deltex-1 in high grade glioma [PDF]
, 2011 Glioblastoma Multiforme is a WHO grade IV brain tumor with glial characteristics leading to more years of life lost than any other cancer. A better understanding of GBM biology and valid animal models are the two key elements to improved therapeutic ...
Huber, Roland Martin
core +1 more source
Effect of notch fillet radius on tensile strength of 817M40 notched bar
IOP Conference Series: Materials Science and Engineering, 2021 Abstract 817M40 steel is a popular grade of hardening alloy steel to its excellent machinability. It is manufactured the mechanical components like gears, shafts, studs and bolts. Its hardness in the range of 248/302 HB. In this paper, notch fillet radius effect on tensile loading was investigated.
Aditya Singh +3 more
openaire +1 more source