Fatigue Crack Growth from Notches: A Numerical Analysis
Applied Sciences, 2020 A numerical approach based on plastic crack tip opening displacement (CTOD) was followed to study fatigue crack growth (FCG) from notches. The identification of fundamental mechanisms was made considering notched and unnotched models, with and without ...
Micael Borges +4 more
doaj +1 more source
Effect of Notch on Strain Rate Concentration Factor of 304 Stainless Steel Bar
Advances in Materials Science and Engineering, 2021 In this study, the notch effect of different types of 304 stainless steel rod notch is studied because of the problem of difficulty in measuring the notch root strain of 304 rod stainless steel, and the parameters of the annular notch root are analyzed ...
Zhengyang Yu +3 more
doaj +1 more source
IKAROS is required for the measured response of NOTCH target genes upon external NOTCH signaling.
PLoS Genetics, 2021 The tumor suppressor IKAROS binds and represses multiple NOTCH target genes. For their induction upon NOTCH signaling, IKAROS is removed and replaced by NOTCH Intracellular Domain (NICD)-associated proteins.
Maud Lemarié +4 more
doaj +1 more source
The effects of notch size and material microstructure on the notch sensitivity factor for notched components [PDF]
Engineering Fracture Mechanics, 2015 Abstract Nickel base superalloys are used in hot sections of gas turbine engines due to its high strength and good creep, fatigue, and corrosion resistance at high temperature. In this paper, a new probabilistic approach based on weakest-link theory that accounts for the effects of the microstructure, notch size and notch acuity is described and ...
Gbadebo Owolabi +4 more
openaire +1 more source
Notch Effect on the Fatigue Behavior of a TC21 Titanium Alloy in Very High Cycle Regime
Applied Sciences, 2018 The very high cycle fatigue (VHCF) property of TC21 titanium alloy blunt-notched specimens were investigated by using an ultrasonic fatigue test machine with a frequency of 20 kHz.
Baohua Nie +5 more
doaj +1 more source
Production Engineering Archives, 2020 Modern methods of testing materials require the use of the latest technologies and combining measurement and calculation methods. It is important to find a quantitative way of describing, among other things, the failures so that it can help to design ...
Macek Wojciech +4 more
doaj +1 more source
Delta-like 4 inhibits choroidal neovascularization despite opposing effects on vascular endothelium and macrophages.: DLL4's opposing effects in choroidal neovascularization [PDF]
, 2012 International audienceInflammatory neovascularization, such as choroidal neovascularization (CNV), occur in the presence of Notch expressing macrophages. DLL4s anti-angiogenic effect on endothelial cells (EC) has been widely recognized, but its influence
Calippe, Bertrand +16 more
core +4 more sources
Influence of the notch-sharpening technique on styrene-acrylonitrile fracture behavior [PDF]
, 2016 The Centre Catala del Plastic and Universidad Rey Juan Carlos laboratories joined forces to investigate the effect of the notch-sharpening technique on the fracture parameters of styrene-acrylonitrile.
Illescas Fernandez, Silvia +4 more
core +2 more sources
Propagation of a magnetic domain wall in magnetic wires with asymmetric notches [PDF]
, 2004 The propagation of a magnetic domain wall (DW) in a submicron magnetic wire consisting of a magnetic/nonmagnetic/magnetic trilayered structure with asymmetric notches was investigated by utilizing the giant magnetoresistance effect.
1000040222327 +14 more
core +4 more sources
MAGP2 Controls Notch via Interactions with RGD Binding Integrins: Identification of a Novel ECM-Integrin-Notch Signaling Axis [PDF]
, 2016 Canonical Notch signaling involves Notch receptor activation via interaction with cell surface bound Notch ligand. Recent findings also indicate that Notch signaling may be modulated by cross-talk with other signaling mechanisms.
Albig, Allan R. +6 more
core +2 more sources