Results 81 to 90 of about 9,549,485 (300)
Cellular Physiology and Biochemistry, 2015 Background/Aims: This study aims to investigate the effect of Luteolin on breast cancer in vitro and in vivo and the interaction between miRNAs and Notch signaling after Luteolin intervention, and illustrates the possible underlying mechanism and ...
Da-Wei Sun +11 more
doaj +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani +10 more
wiley +1 more source
Congenital diseases caused by defective O-glycosylation of Notch receptors [PDF]
, 2018 2018-08The Notch signaling pathway is highly conserved and essential for animal development. It is required for cell differentiation, survival, and proliferation. Regulation of Notch signaling is a crucial process for human health.
Okajima, Tetsuya, Tashima, Yuko
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu +7 more
wiley +1 more source
Intrinsic Notch Effect Leads to Breakdown of Griffith Criterion in Graphene
, 2017 Due to lack of the third dimension in 3D bulk materials, the crack tip in graphene locates on several atoms implying that its fracture behavior can be closely associated with its lattice structure, i.e., the bond length and angle.
Liu, F +3 more
core +1 more source
Advanced Engineering Materials, EarlyView.Low‐temperature imidization of PEG‐modified polyimide enables fully screen‐printed, roll‐to‐roll fabrication of flexible electrodes on PET substrates, delivering robust mechanical durability and reliable ECG/EMG signal performance for wearable electronics.
Akib Abdullah Khan, Jong‐Hoon Kim
wiley +1 more source
Compact Electromagnetic Bandgap Structures for Notch Band in Ultra-Wideband Applications
, 2010 This paper introduces a novel approach to create notch band filters in the front-end of ultra-wideband (UWB) communication systems based on electromagnetic bandgap (EBG) structures.
Jan Sykulski +3 more
core +1 more source
The role of NOTCH2 gene in human malignant glial brain tumours [PDF]
, 2008 Background: Glioblastoma multiforme (GBM), astrocytoma (A) and oligodendroglioma (OG) are the neoplasms of the glial lineage in the Central Nervous System (CNS).
Sivasankaran, Balasubramanian
core +1 more source
Advanced Engineering Materials, EarlyView.Different Al/Al bimetals with a single engineered interface reveal how mechanical mismatch governs fatigue crack growth under cyclic loading. Additionally, loading–unloading–reloading tests link the microyielding behavior to the fatigue crack growth resistance, while crack‐path analysis reveals toughening mechanisms at the interface, highlighting ...
Sebastian Vollath +2 more
wiley +1 more source