Posttranslational modifications in regulating Notch signaling pathway and tumor angiogenesis: from molecular mechanisms to therapeutic applications. [PDF]
J Mol Cell BiolWang J, Zhang M, Wang D.
europepmc +1 more source
The β-Secretase BACE1 Drives Fibroblast Activation in Systemic Sclerosis through the APP/β-Catenin/Notch Signaling Axis [PDF]
McKimmie, Clive Stewart
openalex
Notch Signaling Pathway Interfering as a Possible Asthma Treatment: A Narrative Review
Jingya Wang,1,2,* Kang Yan,3,* Leilei Ma,1,4,* Xianglei Yan,1 Zihan Meng,1 Ji-an Li,1 Meng Wang,1 Chenguang Du,1 Yueyue Yu1 1College of Traditional Chinese Medicine, North China University of Technology, Tangshan, Hebei, People’s Republic of ...
Wang M +8 more
core
American Journal of Botany, EarlyView.Abstract Premise Floral adaptations to pollinators can drive lineage diversification and promote coexistence of species. We investigated the reproductive biology of Satyrium longicolle, a South African orchid that we hypothesized to belong to a long‐proboscid horsefly pollination guild and examined overlap of pollinators and floral traits among ...
Steven D. Johnson +3 more
wiley +1 more source
The Role of the Gut Microbiota in Allogeneic Hematopoietic Cell Transplantation
American Journal of Hematology, EarlyView.ABSTRACT Allogeneic hematopoietic cell transplantation (allo‐HCT) is an effective treatment for patients with high‐risk hematologic malignancies. Over the last decade, gut microbiota composition during allo‐HCT has been associated with patients' outcomes.
Wenjing Hao +4 more
wiley +1 more source
Erratum: Notch signaling induces epithelial-mesenchymal transition to promote invasion and metastasis in adenoid cystic carcinoma. [PDF]
Am J Transl ResZhao ZL +10 more
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Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases
Animal Models and Experimental Medicine, EarlyView.Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam +4 more
wiley +1 more source
Recombinant ADAMTS‑1 promotes muscle regeneration accompanied by downregulation of Notch signaling. [PDF]
Int J Mol MedKim JH +10 more
europepmc +1 more source
SDPR–STK38 axis controls the proliferation–differentiation balance in alveolar type II cells
Animal Models and Experimental Medicine, EarlyView.The present study identifies SDPR as a pivotal regulator orchestrating the balance between proliferation and differentiation in alveolar type II (AT2) cells. In SDPR+/+ cells, SDPR binds to and inhibits STK38 activity, thereby sustaining GSK‐3β signaling functionality to promote cyclin D1 degradation and maintain cell cycle homeostasis.
Jie Wang +6 more
wiley +1 more source