Results 241 to 250 of about 133,611 (360)

Notch Signaling [PDF]

open access: yesDevelopmental Cell, 2003
openaire   +1 more source

IKKβ and USP28 Regulate HEY1 Stability to Promote Cancer Stemness and Immune Evasion in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
The uncovered IKKβ‐USP28‐HEY1 axis fuels cancer stemness and immune evasion in hepatocellular carcinoma. USP28 deubiquitinates HEY1 upon IKKβ‐mediated phosphorylation, conferring PD‐1/PD‐L1 blockade resistance. Pharmacological inhibition of USP28 sensitizes resistant tumors to anti‐PD‐1 immunotherapy, revealing a promising therapeutic strategy ...
Na Shao   +8 more
wiley   +1 more source

Notch signaling enhances PASMC proliferation and vascular remodeling in CTEPH. [PDF]

open access: yesOpen Life Sci
Aimaier S   +5 more
europepmc   +1 more source

Surfaceome Reprogramming of Stemsomes Promotes Lung Cancer Targeting via Potentiated Receptor–Ligand Interactions

open access: yesAdvanced Science, EarlyView.
This study presents a surfaceome‐reprogramming strategy for mutation‐independent lung cancer therapy by repurposing dexamethasone to prime mesenchymal stem cell‐derived nanovesicles. The engineered vesicles leverage multi‐valent interactions mediated by upregulated adhesion proteins, EPHA2, and NOTCH3.
Geunhye Kim   +8 more
wiley   +1 more source

Correction: The novel Chinese medicine JY5 formula alleviates hepatic fibrosis by inhibiting the notch signaling pathway. [PDF]

open access: yesFront Pharmacol
Fu Y   +16 more
europepmc   +1 more source

Notch signaling without the APH-2/nicastrin subunit of gamma secretase in Caenorhabditis elegans germline stem cells

open access: green
David M. Brinkley   +9 more
openalex   +2 more sources

Notch signaling. [PDF]

open access: yesClinical Cancer Research, 2006
openaire   +2 more sources

One‐Step Preparation of Lanthanide‐Doped Polyurea Multicolor Microspheres for Versatile Fluorescent Applications

open access: yesAdvanced Science, EarlyView.
Lanthanide‐doped polyurea microspheres are prepared via a facile one‐step precipitation polymerization. They exhibit strong hydrogen‐bonding and coordination interactions with excellent properties, including multicolor emission, high quantum yield (75.3%), remarkable stability, redispersibility, and biocompatibility.
Guiyu Zhang   +9 more
wiley   +1 more source

Common Coronary Artery Disease Risk Variants in Endothelial Regulatory Elements Modulate Tetraspanin 14 Expression and Notch Signaling. [PDF]

open access: yesArterioscler Thromb Vasc Biol
Lee-Kim VS   +14 more
europepmc   +1 more source

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