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Predicted Effects of Patient Variability and Notch Signaling on In Situ Vascular Tissue Engineering. [PDF]
Ann Biomed Engvan Asten JGM +4 more
europepmc +1 more source
Mac-/Lactosylceramide regulates intestinal homeostasis and secretory cell fate commitment by facilitating Notch signaling. [PDF]
ElifeTang K +8 more
europepmc +1 more source
Statement of Retraction: Toll-like receptor 3 gene regulates cataract-related mechanisms via the Jagged-1/Notch signaling pathway. [PDF]
Bioengineeredeuropepmc +1 more source
Correction to "Inhibition of the Numb/Notch Signaling Pathway Increases Radiation Sensitivity in Human Nasopharyngeal Carcinoma Cells". [PDF]
Kaohsiung J Med Scieuropepmc +1 more source
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Annual Review of Biophysics, 2021
Notch signaling is a conserved system of communication between adjacent cells, influencing numerous cell fate decisions in the development of multicellular organisms. Aberrant signaling is also implicated in many human pathologies. At its core, Notch has a mechanotransduction module that decodes receptor–ligand engagement at the cell surface under ...
David Sprinzak, Stephen C Blacklow
exaly +3 more sources
Notch signaling is a conserved system of communication between adjacent cells, influencing numerous cell fate decisions in the development of multicellular organisms. Aberrant signaling is also implicated in many human pathologies. At its core, Notch has a mechanotransduction module that decodes receptor–ligand engagement at the cell surface under ...
David Sprinzak, Stephen C Blacklow
exaly +3 more sources
Notch signaling in reproduction
Trends in Endocrinology & Metabolism, 2021The Notch signaling pathway is conserved among mammalian species and controls proliferation, differentiation, and cell death in many organs throughout the body including the reproductive tract. Notch signaling plays critical roles in the development and function of both the male and female reproductive systems.
Genna E. Moldovan +2 more
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Science, 1995
The Notch/Lin-12/Glp-1 receptor family mediates the specification of numerous cell fates during development in Drosophila and Caenorhabditis elegans . Studies on the expression, mutant phenotypes, and developmental consequences of unregulated receptor activation have implicated these proteins
S, Artavanis-Tsakonas +2 more
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The Notch/Lin-12/Glp-1 receptor family mediates the specification of numerous cell fates during development in Drosophila and Caenorhabditis elegans . Studies on the expression, mutant phenotypes, and developmental consequences of unregulated receptor activation have implicated these proteins
S, Artavanis-Tsakonas +2 more
openaire +2 more sources
Notch signaling in lymphopoiesis
Seminars in Immunology, 2003Notch signaling regulates many cell fate decisions during development of multi-cellular organisms. Signals initiated by Notch influence a wide variety of processes that include lineage specification, cell survival and proliferation, and border formation.
Warren S, Pear, Freddy, Radtke
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Seminars in Cell & Developmental Biology, 1998
In addition to the core components of the Notch pathway, a number of proteins have been identified that exert positive or negative influences on Notch signaling. These include extracellular modulators, which may influence binding or activation of Notch by its ligands, cytoplasmic modulators, which presumably influence signal transduction steps after ...
V M, Panin, K D, Irvine
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In addition to the core components of the Notch pathway, a number of proteins have been identified that exert positive or negative influences on Notch signaling. These include extracellular modulators, which may influence binding or activation of Notch by its ligands, cytoplasmic modulators, which presumably influence signal transduction steps after ...
V M, Panin, K D, Irvine
openaire +2 more sources