Results 161 to 170 of about 156,496 (347)

SnapShot: Notch Signaling Pathway

Cell, 2007
Ilagan, Ma. Xenia G., Kopan, Raphael
openaire   +2 more sources

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You, Jaewoo Park, Jung Yeon Jang, Junho Noh, Jaehyun Lee, Geunho Kwon, Myeong Sang Yu, Yoo‐Sam Chung, Seung‐Jun Lee, Keunsoo Kang, Jihwan Park, Ji Heui Kim, Kyuho Kang   +12 more
wiley   +1 more source

Novel insights into Notch signaling in tumor immunity: potential targets for cancer immunotherapy

Frontiers in Immunology
Notch signaling pathway is a highly conserved system of cell-to-cell communication that participates in various biological processes, such as stem cell maintenance, cell fate decision, cell proliferation and death during homeostasis and development ...
Man Wang, Fei Yu, Yuan Zhang, Peifeng Li
doaj   +1 more source

Astragalus Polysaccharide RAP Induces Macrophage Phenotype Polarization to M1 via the Notch Signaling Pathway [PDF]

, 2019
Wei Wei, Zhipeng Li, Zhaoxiang Bian, Quan‐Bin Han   +3 more
openalex   +1 more source

Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy

Advanced Science, EarlyView.
This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao, Qingqing Zhou, Mengli Li, Wen Zou, Zhenzhong Zhang, Jinjin Shi, Junjie Liu   +6 more
wiley   +1 more source

Exposure to PM2.5 affects blood lipid levels in asthmatic rats through notch signaling pathway [PDF]

, 2019
Tianrong Zhang, Yan Zheng, Yizhen Gao, Tianyang Zhao, Shuangyu Guo, Liwei Yang, Yanbin Shi, Liting Zhou, Lin Ye   +8 more
openalex   +1 more source

Genomics Insights Into High‐Latitude Adaptation of Tibetan Macaques

Advanced Science, EarlyView.
Tibetan macaques exhibit unique adaptations to cold, high‐latitude environments, including shortened tails and enhanced fat storage. Genomic analyses reveal a species‐specific TBX6 mutation linked to tail reduction and selection on lipid metabolism genes.
Rusong Zhang, Ying Hu, Yang Teng, Jiwei Qi, Yangzhen Ciren, Lin Zhang, Qiao Du, Wencai Xu, Liang Zhou, Zhenxin Fan, Jinchuan Xing, Ming Li, Jing Li   +12 more
wiley   +1 more source

Correction: Repression of Ccr9 Transcription in Mouse T Lymphocyte Progenitors by the Notch Signaling Pathway [PDF]

, 2015
Veena Krishnamoorthy, Tiffany Carr, Renée F. de Pooter, Akinola Olumide Emanuelle, Fotini Gounari, Barbara L. Kee   +5 more
openalex   +1 more source

Supplementary Figures 1-3, Tables 1-2 from Downregulation of Notch Pathway by a γ-Secretase Inhibitor Attenuates AKT/Mammalian Target of Rapamycin Signaling and Glucose Uptake in an ERBB2 Transgenic Breast Cancer Model

, 2023
Clay L. Efferson, Christopher T. Winkelmann, Christopher Ware, Timothy J. Sullivan, Saverio Giampaoli, Jennifer Tammam, Shailendra B. Patel, Giuseppe Mesiti, John F. Reilly, Raymond E. Gibson, Carolyn A. Buser, Timothy J. Yeatman, Domenico Coppola, Christopher Winter, Edwin Clark, Giulio Draetta, Peter R. Strack, Pradip K. Majumder   +17 more
openalex   +1 more source

Notch2 Directs aTreg Cell Fate toward Immunoregulation or Inflammatory Pyroptosis

Advanced Science, EarlyView.
Schematic illustration showing that the Notch2 intracellular domain (NICD2) facilitates pyroptosis resistance in activated Tregs through the RREB1/Foxo1 signaling pathway. In addition, Notch2‐mediated pyroptosis resistance in activated Tregs promotes immunoregulatory capacity, thereby attenuating Th2‐driven inflammatory responses in allergic rhinitis ...
Yue‐Long Qiao, Shan Xu, You Zou, Rui Yang, Han Zheng, Jia‐Yu Liu, Hui‐Ming Fan, Yuan‐Yuan Zhang, Yong‐Gang Kong, Wo‐Er Jiao, Shi‐Ming Chen   +10 more
wiley   +1 more source