Results 161 to 170 of about 152,934 (201)

Multifaceted analysis of noncoding and coding de novo variants implicates NOTCH signaling pathway in tetralogy of Fallot in Chinese population. [PDF]

HGG Adv
Lin Q, Zhang D, Gruber PJ, Tam PK, Lui VC, Wu Z, Hong H, Chien KR, Sham PC, Tang CS.   +9 more
europepmc   +1 more source

Evolution and Function of the Notch Signaling Pathway: An Invertebrate Perspective. [PDF]

Int J Mol Sci
Lv Y, Pang X, Cao Z, Song C, Liu B, Wu W, Pang Q.   +6 more
europepmc   +1 more source

[Retracted] Effects of RUNX3 mediated Notch signaling pathway on biological characteristics of colorectal cancer cells. [PDF]

Int J Oncol
Li H, Li D, Meng N.
europepmc   +1 more source

TRIM59/RBPJ positive feedback circuit confers gemcitabine resistance in pancreatic cancer by activating the Notch signaling pathway. [PDF]

Cell Death Dis
Chen S, He Z, Cai K, Zhang Y, Zhu H, Pang C, Zhang J, Wang D, Xu X.   +8 more
europepmc   +1 more source

Notch signaling pathways inthe obese mouse

Publikationer från Örebro universitet, 2017
openaire   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Notch signalling: a simple pathway becomes complex

Nature Reviews Molecular Cell Biology, 2006
A small number of signalling pathways are used iteratively to regulate cell fates, cell proliferation and cell death in development. Notch is the receptor in one such pathway, and is unusual in that most of its ligands are also transmembrane proteins; therefore signalling is restricted to neighbouring cells.
Sarah Bray
openaire   +4 more sources

Notch signaling pathway in pancreatic tumorigenesis

2023
The Notch signaling pathway is an evolutionary conserved signal transduction cascade that is critical to embryonic and postnatal development, but aberrant Notch signaling is also implicated in tumorigenesis of many organs including the pancreas. Pancreatic ductal adenocarcinoma (PDAC) is the most common malignancy in the pancreas, with a dismally low ...
Wen-Cheng, Chung, Keli, Xu
openaire   +2 more sources

Notch Signaling Pathway

Science's STKE, 2006
Notch is a receptor that mediates intercellular signaling through a pathway conserved across the metazoa. It is involved in cell fate assignation and pattern formation during development. The receptor acts as a membrane-tethered transcription factor and is activated by members of the Delta, Serrate, Lag-2 family of Notch ligands, which trigger two ...
Matthias, Ehebauer, Penelope, Hayward, Alfonso, Martinez-Arias   +2 more
openaire   +2 more sources

Notch signalling pathway and human diseases

Seminars in Cell & Developmental Biology, 1998
Several homologs of the Drosophila Notch receptor and its ligands, Delta/Serrate, have been cloned in man. Three human disorders including a neoplasia (a T-cell acute lymphoblastic leukemia/lymphoma), a late onset neurological disease (CADASIL) and a developmental disorder (the Alagille syndrome) are associated with mutations in, respectively, the ...
A, Joutel, E, Tournier-Lasserve
openaire   +2 more sources

Notch signaling pathway and tissue engineering

Frontiers in Bioscience, 2007
The Notch pathway is a signaling network essential for proper organ development in an embryo, and is indispensable for tissue regeneration in the adult. This key regulatory signaling network is evolutionarily conserved in all metazoans and is continually utilized for the building, maintenance and repair of diverse organs and tissues.
Morgan E, Carlson, Matthew S, O'Connor, Michael, Hsu, Irina M, Conboy   +3 more
openaire   +2 more sources