Results 61 to 70 of about 21,410 (192)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

NOTICING AND TEXT-BASED CHAT [PDF]

open access: yes, 2006
This study examined the capacity of text-based online chat to promote learners’ noticing of their problematic language productions and of the interactional feedback from their interlocutors. In this study, twelve ESL learners formed six mixed-proficiency
Yong Zhao   +5 more
core   +2 more sources

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

“Keeping an Eye Out”: Students’ Experiences of School Personnel’s Noticing in Shaping or Hindering a Positive School Climate

open access: yesSocial Sciences
A positive school climate is characterized by a higher degree of well-being among students, reduced bullying, and improved academic performance. While many initiatives are aimed at creating a positive school climate, discussions in both research and ...
Silvia Edling   +5 more
doaj   +1 more source

УЗКОСПЕЦИАЛИЗИРОВАННОЕ ЧТЕНИЕ КАК ИНСТРУМЕНТ УПРАВЛЕНИЯ ЯЗЫКОВЫМИ ЗНАНИЯМИ ПЕРЕВОДЧИКА

open access: yesНаучно-педагогическое обозрение, 2022
Рассматривается вопрос самостоятельной подготовки переводчика к профессиональной деятельности, в частности расширения своих языковых знаний и обеспечения аутентичности речи на иностранном языке в рамках определенной предметной области.
Емельянова Яна Борисовна
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Teacher Expertise and Professional Vision: Examining Knowledge-Based Reasoning of Pre-Service Teachers, In-Service Teachers, and School Principals

open access: yesFrontiers in Education, 2020
Classroom professional vision is a teaching skill that refers to the ability of teachers to rapidly notice information in class and engage in knowledge-based reasoning about the noticed information.
Andreas Gegenfurtner   +7 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

In-Service Mathematics Teacher’s Professional Noticing of Exemplary Video Lessons Through Two Frameworks: An Exploratory Study in China

open access: yesECNU Review of Education
Purpose This study aims to investigate the noticing ability of Chinese in-service mathematics teachers (ISTs) when observing exemplary mathematics lessons online using two different noticing frameworks. Design/Approach/Methods The noticing of 24 ISTs was
Kexin Chen (陈可欣)   +3 more
doaj   +1 more source

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