Results 51 to 60 of about 21,410 (192)

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Teacher noticing in language and literacy landscapes of practice

open access: yes, 2019
This chapter demonstrates what happened when experienced teachers in Scotland began to navigate a wider range of knowledge domains and epistemologies to better understand and address the literacy attainment gap associated with poverty.
Ellis, Sue   +7 more
core   +1 more source

Exploring the terrains of mathematics teacher noticing

open access: yes, 2021
Noticing is a crucial part of any teachers’ classroom practices. Given its importance, research in teacher noticing has gained traction and has significantly increased in recent years.
Schack, Edna O.   +3 more
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Is noticing an answer to the problem of unacquirable structures in the second language?

open access: yesStellenbosch Papers in Linguistics Plus, 2002
The aim of this article is to evaluate one proposed solution to the problem that some aspects of a second language (L2) seem unacquirable. In order to understand the solution, it is necessary to explicate the problem.
Southwood, Frenette
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Grunnskolelærerstudenters ferdigheter i profesjonell analytisk observasjon etter en lesson study-syklus

open access: yesUniped
I studien blir det undersøkt hvordan grunnskolelærerstudenter i fjerde studieår uttrykker ferdigheter i profesjonell analytisk observasjon (PAO; noticing) gjennom erfaringsdeling fra en lesson study-syklus i matematikkundervisning.
Karin Landschulze
doaj   +1 more source

The practice of noticing and wondering within school–university partnerships [PDF]

open access: yesPDS Partners
PurposeThe purpose of this viewpoint article is to share reflective narratives of school–university partnership collaborators on the benefits of integrating the pedagogical practice of noticing and wondering and the Noticing and Wondering Protocol into ...
Kristin E. Harbour   +4 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Mathematics Teacher Noticing [PDF]

open access: yes, 2011
Mathematics Teacher Noticing is the first book to examine research on the particular type of noticing done by teachers---how teachers pay attention to and make sense of what happens in the complexity of instructional situations.

core   +2 more sources

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