Results 141 to 150 of about 882,347 (341)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

INVERSE TENSOR TRANSFER FOR NOVEL VIEW SYNTHESIS [PDF]

, 2008
This paper provides a new transfer based novel view synthesis method. This method does not need a pre-computed dense depth map, therefore overcomes most common problems associated with conventional dense correspondence algorithms, yet still produce very ...
Hongdong Li, Richard Hartley
core  

Novel View Synthesis Under Large-Deviation Viewpoint for Autonomous Driving [PDF]

Novel view synthesis is a critical task in autonomous driving. Although 3D Gaussian Splatting (3D-GS) has shown success in generating novel views, it faces challenges in maintaining high-quality rendering when viewpoints deviate significantly from the ...
Xu, Shibiao, Pan, Chengwei, Ma, Xin, Zhang, Jiguang, Lu, Peng   +4 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

3D reconstruction for unconstrained image collections using Gaussian Splatting with foundation model

Geo-spatial Information Science
Achieving high-quality rendering with Gaussian Splatting for unconstrained image collections is critical for advancing 3D reconstruction. Currently, the methods using a single multi-layer perceptron and convolutional neural network to predict distractors
Shuowen Huang, Qingwu Hu, Pengcheng Zhao, Mingyao Ai, Xujie Zhang, Wenwu Ou, Linze Li   +6 more
doaj   +1 more source

Enhancing Neural Radiance Fields with Adaptive Multi-Exposure Fusion: A Bilevel Optimization Approach for Novel View Synthesis

AAAI Conference on Artificial Intelligence
Neural Radiance Fields (NeRF) have made significant strides in the modeling and rendering of 3D scenes. However, due to the complexity of luminance information, existing NeRF methods often struggle to produce satisfactory renderings when dealing with ...
Yang Zou, Xingyuan Li, Zhiying Jiang, Jinyuan Liu   +3 more
semanticscholar   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

NVS-GAN: Benefit of generative adversarial network on novel view synthesis

International Journal of Intelligent Networks
The methodology to generate new views for an object from provided input object view is called Novel View Synthesis (NVS). Humans imagine novel views through prior knowledge gathered through their lifetime.
H.S. Shrisha, V. Anupama
doaj   +1 more source