Results 91 to 100 of about 7,315 (135)

ARPE-19-A Stable Cell Line Expressing a Variant of Unknown Significance in the <i>NPC1</i> Gene. [PDF]

Genes (Basel)
Monteiro B, Peixoto MI, Ortigoza-Escobar JD, Alves M, Sandiares AC, Gonçalves M, Moreira LV, Coutinho MF, Matos L, Alves S, Encarnação M.   +10 more
europepmc   +1 more source

APOE3 astrocytes can rescue lipid abnormalities and dystrophic neurites of APOE4 human neurons. [PDF]

PNAS Nexus
Halim DO, Di Biase E, Rajon A, Jordi L, Hallett PJ, Isacson O.   +5 more
europepmc   +1 more source

Small Molecules to Elevate Rab7-GTPase Activity and Lower Cholesterol Accumulation in Niemann-Pick Type C Disease. [PDF]

Pharm Res
Nguyen MKL, Nikenich MR, Seifert K, Pinkenburg C, Lai F, Walther HL, Hartmann M, Szulc A, Sparkes E, Chen S, Wikramanayake R, Bernaus-Esqué M, Liu Y, Tebar F, Serwetnyk M, Wenninger A, Patzke C, Blagg BSJ, Ashfeld BL, Groundwater PW, Hibbs DE, Hoy AJ, Rentero C, Enrich C, Cho AN, Du JJ, Grewal T.   +26 more
europepmc   +1 more source

AI-guided multi-omics analysis identifies NPC1-modulated susceptibility to SARS-CoV-2 infection under PM_2.5 exposure. [PDF]

Nat Commun
Feng G, Dong Z, Ke L, Zhou W, Tian Y, Li X, Xiang W, Li Y, Huang Q, Liu L, Yin B, Yan S, Liu J, Ma X, Chen H, He M, Hao K, Liu S, Di Q.   +18 more
europepmc   +1 more source

Mechanistic Basis of Cholesterol Binding and Transfer in NPC2: Insights From Molecular Dynamics Simulations. [PDF]

Chembiochem
Patel S, Elghobashi-Meinhardt N.
europepmc   +1 more source

How endosomal PIKfyve inhibition prevents viral membrane fusion and entry. [PDF]

Proc Natl Acad Sci U S A
Chow N, Scanavachi G, Saminathan A, Kirchhausen T.   +3 more
europepmc   +1 more source

A Cross-Disease Microglial Transcriptional Program Characterizes Neurodegeneration and Highlights SPP1 as a Biomarker. [PDF]

Glia
Palma A, Stefanelli R, Trenta F, Projetti C, Massa G, Canterini S, Fiorenza MT.   +6 more
europepmc   +1 more source

CTSS regulates macrophage lipid metabolic reprogramming and white matter repair after intracerebral hemorrhage. [PDF]

J Transl Med
Yu X, Huang H, Mao D, Wu J, Pan J, Kuang Y, Wu Y, Chen H, Fan L, Zheng Y, Zhou J, Jiang S, Wu X, Zhou H, Yan W, Zheng H, Chen J, Chen G, Gu C.   +18 more
europepmc   +1 more source

Extracellular vesicles in Niemann pick disease type C: current knowledge and future opportunities. [PDF]

Front Cell Neurosci
Hawthorne SCB, Sandau US, Saugstad JA.
europepmc   +1 more source