Results 101 to 110 of about 7,315 (135)

Revealing the Shared Genetic Architecture of Metabolic Dysfunction-Associated Steatotic Liver Disease-Related Traits Through Genomic Structural Equation Modeling. [PDF]

Genet Epidemiol
Dong H, Li Y, Ding Q, Zhang M, Gu S, Liu M.   +5 more
europepmc   +1 more source

NPC1 trafficking via VPS41-dependent LAMP carriers regulates endosomal cholesterol homeostasis. [PDF]

Proc Natl Acad Sci U S A
Ndoj K, Tantucci M, Sanza P, Zubak K, Marodin G, Kingma J, Snijder F, Veenendaal T, Kober DL, Zelcer N, Klumperman J.   +10 more
europepmc   +1 more source

Identification of autophagy-related key biomarkers in caerulein induced acute pancreatitis: In silico and in vivo study. [PDF]

PLoS One
Shen X, Yao J, Wang Z, Chen R, Li L, Xu X, Huang Y.   +6 more
europepmc   +1 more source

Comparison of neonatal systemic and intracerebroventricular AAV9 gene therapy delivery demonstrating improved behavioral and phenotypic outcomes in a mouse model of Niemann-Pick disease, type C1. [PDF]

PLoS One
Epstein BE, Soden GM, Incao AA, Mylvara A, Flynn J, Ozsolak F, Pavan WJ.   +6 more
europepmc   +1 more source

Early Diagnosis of Nieman-Pick Disease Type C and Rapid Response of Gelastic Cataplexy to Treatment With N-Acetyl-L-Leucine: A Case Report. [PDF]

Am J Case Rep
Rojnueangnit K, Puttamanee S, Intarakhao S, Khusiwilai K.   +3 more
europepmc   +1 more source

LASER couples damage sensing to ESCRT assembly for lysosome repair. [PDF]

Nature
Goul CS, Jain A, Yitiz S, Soltani ZE, Yang S, Rapp S, Spacci M, Federman S, Sacco J, Li H, Enriquez LD, Liv N, Przybyla L, Zoncu R.   +13 more
europepmc   +1 more source

Targeting Pathways Implicated in Cholesterol Metabolism for Novel Cancer Therapy. [PDF]

Cancers (Basel)
Zhou Y, Sharma V, Li X, Singla RK, Kumar A, Kyada A, Ballal S, Nathiya D, Koul A, Khalid M, Gulati M, Arora S, Behl T, Kavalakatt J, Shen B, Bishayee A.   +15 more
europepmc   +1 more source

From Neonatal Cholestasis to Progressive Neurological Impairment: A Case of Niemann-Pick Disease Type C. [PDF]

Cureus
Carvalho de Sousa L, Gomes Pereira C, Magalhães C.   +2 more
europepmc   +1 more source

Cholesterol maintains the degradative capacity of lysosomes during clearance and recycling of dysfunctional mitochondria. [PDF]

Nat Commun
Yang H, Matsuhisa K, Wei M, Nishi W, Koh DHZ, Sim AY, Bonne I, Saheki Y.   +7 more
europepmc   +1 more source

Benchmarking Classical and Quantum Machine Learning for Potency Prediction across Ten Therapeutically Relevant Targets. [PDF]

ACS Med Chem Lett
Garg S, Garg S.
europepmc   +1 more source