Results 211 to 220 of about 7,302 (251)

Cholesin mRNA Expression in Human Intestinal, Liver, and Adipose Tissues. [PDF]

Nutrients
Gilliam-Vigh H, Suppli MP, Heimbürger SMN, Lund AB, Knop FK, Ellegaard AM.   +5 more
europepmc   +1 more source

Microbiota-derived 3-Methyl-L-histidine mediates the proatherogenic effect of high chicken protein diet. [PDF]

MedComm (2020)
Zhu S, Liu L, Zhao Y, Ye B, He J, Li W, Xu Y, Zhu J, Xia M, Liu Y.   +9 more
europepmc   +1 more source

Associations between lipid-lowering drugs and urate and gout outcomes: a Mendelian randomization study. [PDF]

Front Endocrinol (Lausanne)
Liu M, Yin N, Zhu Y, Du A, Cai C, Leng P.   +5 more
europepmc   +1 more source

Lipid-Lowering Drugs and Pulmonary Vascular Disease: A Mendelian Randomization Study. [PDF]

Pulm Circ
Yuan X, Hong P, Zhou J.
europepmc   +1 more source

Cardiometabolic drugs and kidney function – a drug target Mendelian randomisation study

Andries A, Bennett SM, Walker V, Heid IM, Köttgen A, Gorski M, Briasouli A, Zheng J, Hveem K, Hallan SI, Åsvold BO, Gaunt T, Brumpton BM, Rasheed H.   +13 more
europepmc   +1 more source

The Niemann-Pick C1 Like 1 (NPC1L1) Inhibitor Ezetimibe Improves Metabolic Disease Via Decreased Liver X Receptor (LXR) Activity in Liver of Obese Male Mice(要約)

太一 杉﨑
openalex   +1 more source

A snp of NPC1L1 affects cholesterol absorption in Japanese

A snp of NPC1L1 affects cholesterol absorption in Japanese
openaire  

Structural insights into the mechanism of human NPC1L1-mediated cholesterol uptake [PDF]

Science Advances, 2021
Structures of NPC1L1 reveal how NPC1L1 senses the cholesterol level by conformational changes of the sterol-sensing domain.
Miaoqing Hu, Fan Yang, Yawen Huang
exaly   +3 more sources

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Dissecting NPC1L1-mediated cholesterol absorption

Future Lipidology, 2008
Wei Qi & Bao-Liang Song† †Author for correspondence Chinese Academy of Sciences, The State Key Laboratory of Molecular Biology, Institute of Biochemistry & Cell Biology, Shanghai Institutes for Biological Sciences, China Tel.: +86 215 492 1649; Fax: +86 215 492 1649; blsong@sibs.ac.cn ‘...NPC1L1 is critical for dietary cholesterol absorption and is ...
Wei Qi, Bao-Liang Song
openaire   +1 more source

Human NPC1L1 Expression is Positively Regulated by PPARα

Pharmaceutical Research, 2010
Niemann-Pick C1-like 1 (NPC1L1), a pharmacological target of ezetimibe, is responsible for cholesterol absorption in enterocytes and hepatocytes. In the present study, the involvement of peroxisome proliferator-activated receptor α (PPARα) and its cofactor, PPARγ coactivator 1α (PGC1α) in the transcriptional regulation of human NPC1L1 was analyzed ...
Yuki, Iwayanagi, Tappei, Takada, Fumiya, Tomura, Yoshihide, Yamanashi, Tomohiro, Terada, Ken-ichi, Inui, Hiroshi, Suzuki   +6 more
openaire   +2 more sources